ArticleScientific reports2014
Inertial particle separation by differential equilibrium positions in a symmetrical serpentine micro-channel.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
54 citing papers in PubMed.
- Ridge-assisted micro positioning of cells in a channel.Science advances · 2026Article
- Efficient methods of isolation and purification of extracellular vesicles.Nano convergence · 2025Review
- Superparamagnetic Bead-Based Microfluidic Fluoroimmunoassay Platform for Rapid Ochratoxin A Detection in Flour.ACS sensors · 2025Article
- Effects of Shear and Extensional Stresses on Cells: Investigation in a Spiral Microchannel and Contraction-Expansion Arrays.ACS biomaterials science & engineering · 2025Review
- Fabrication of a Spiral Microfluidic Chip for the Mass Production of Lipid Nanoparticles Using Laser Engraving.Micromachines · 2025Article
- Deciphering the Evolution of Inertial Migration in Serpentine Channels.Analytical chemistry · 2024Article
- Computational and experimental microfluidics: Total analysis system for mixing, sorting, and concentrating particles and cells.APL bioengineering · 2024Article
- Novel Isolating Approaches to Circulating Tumor Cell Enrichment Based on Microfluidics: A Review.Micromachines · 2024Review
- Human leucocytes processed by fast-rate inertial microfluidics retain conventional functional characteristics.Journal of the Royal Society, Interface · 2024Article
- Enhancing particle focusing: a comparative experimental study of modified square wave and square wave microchannels in lift and Dean vortex regimes.Scientific reports · 2024Article
- Pneumatically Driven Microfluidic Platform and Fully Automated Particle Concentration System for the Capture and Enrichment of Pathogens.ACS omega · 2023Article
- Asymmetrical Obstacles Enable Unilateral Inertial Focusing and Separation in Sinusoidal Microchannel.Cyborg and bionic systems (Washington, D.C.) · 2023Article
- Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood.Bioengineering & translational medicine · 2022Article
- Inertial focusing of particles and cells in the microfluidic labyrinth device: Role of sharp turns.Biomicrofluidics · 2022Article
- Scaling microfluidic throughput with flow-balanced manifolds to simply control devices with multiple inlets and outlets.Biomicrofluidics · 2022Article
- Numerical investigation of the formation and stability of homogeneous pairs of soft particles in inertial microfluidics.Journal of fluid mechanics · 2022Article
- Separation of U87 glioblastoma cell-derived small and medium extracellular vesicles using elasto-inertial flow focusing (a spiral channel).Scientific reports · 2022Article
- 3D-Stacked Multistage Inertial Microfluidic Chip for High-Throughput Enrichment of Circulating Tumor Cells.Cyborg and bionic systems (Washington, D.C.) · 2022Article
- Amalgamation of diverse hydrodynamic effects with novel triple-sided membrane valves for developing a microfluidic device for filterless and continuous water purification.RSC advances · 2021Article
- Dielectrophoresis Separation of Platelets Using a Novel Zigzag Microchannel.Micromachines · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents an inertial microfluidic device with a simple serpentine micro-channel to continuously separate particles with high performance. Separation of micro/nano-particles has a variety of potential applications in biomedicine and industry. Among the existing separation technologies, a label-free technique without the use of antibody affinity, filter or centrifugation is highly desired to ensure minimal damage and alteration to the cells. Inertial microfluidics utilising hydrodynamic forces to separate particles is one of the most suitable label-free technologies with a high throughput. Our separation concept relies on size-based differential equilibrium positions of the particles perpendicular to the flow. Highly efficient separation is demonstrated with particles of different sizes. The results indicate that the proposed device has an integrative advantage to the existing microfluidic separation techniques, taking accounts of purity, efficiency, parallelizability, footprint, throughput and resolution. Our device is expected to be a good alternative to conventional separation methods for sample preparation and clinical diagnosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.