Evidence map›Paper›PMID 24681586›Full record

Trial reportPsychological science2014

Testosterone reactivity to provocation mediates the effect of early intervention on aggressive behavior.

Justin M Carré, Anne-Marie R Iselin, Keith M Welker, Ahmad R Hariri, Kenneth A Dodge

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychological science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Hostile attributional bias and aggressive behavior in global context.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  7. Review
  8. Honest Signals of Status: Facial and Bodily Dominance Are Related to Success in Physical but Not Nonphysical Competition.Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Justin M Carré1Department of Psychology, Nipissing University.
Anne-Marie R Iselin
Keith M Welker
Ahmad R Hariri
Kenneth A Dodge

Funding

TRANSLATION AND DISSEMINATION COREP30DA023026 · NIDA · DUKE UNIVERSITY · PI HOYLE, RICK · 2008 to 2023
$19.6M
Optimizing Prevention of Costly Adult OutcomesR01DA016903 · NIDA · DUKE UNIVERSITY · PI CROWLEY, DANIEL MAX, DODGE, KENNETH A · 2003 to 2019
$10.2M
Self-Regulation Failure: Identifying and Modifying a Risk PhenotypeR01DA031579 · NIDA · DUKE UNIVERSITY · PI HARIRI, AHMAD R., STRAUMAN, TIMOTHY J · 2010 to 2012
$1.9M
Neurogenetic Pathways to Drug Use in Young AdultsR01DA033369 · NIDA · DUKE UNIVERSITY · PI HARIRI, AHMAD R. · 2013 to 2016
$1.4M
Adolescent Drug Use: Development, Prevention, and PolicyK05DA015226 · NIDA · DUKE UNIVERSITY · PI DODGE, KENNETH A · 2002 to 2012
$1.2M
NIDA NIH HHS K05 DA015226NIDA NIH HHS K05DA15226NIDA NIH HHS P30 DA023026NIDA NIH HHS P30DA023026NIDA NIH HHS R01 DA016903NIDA NIH HHS R01DA016903NIDA NIH HHS R01 DA031579NIDA NIH HHS R01DA031579NIDA NIH HHS R01 DA033369NIDA NIH HHS R01DA033369
6 · The paper itself

Abstract

We tested the hypotheses that the Fast Track intervention program for high-risk children would reduce adult aggressive behavior and that this effect would be mediated by decreased testosterone responses to social provocation. Participants were a subsample of males from the full trial sample, who during kindergarten had been randomly assigned to the 10-year Fast Track intervention or to a control group. The Fast Track program attempted to develop children's social competencies through child social-cognitive and emotional-coping skills training, peer-relations coaching, academic tutoring, and classroom management, as well as training for parents to manage their child's behavior. At a mean age of 26 years, participants responded to laboratory provocations. Results indicated that, relative to control participants, men assigned to the intervention demonstrated reduced aggression and testosterone reactivity to social provocations. Moreover, reduced testosterone reactivity mediated the effect of intervention on aggressive behavior, which provides evidence for an enduring biological mechanism underlying the effect of early psychosocial intervention on aggressive behavior in adulthood.

Indexed as

Adaptation, PsychologicalAdultAggressionAntisocial Personality DisorderChildCognitive Behavioral TherapyEarly Intervention, EducationalHumansMaleNegotiatingSchoolsTestosteroneTestosteroneaggressive behaviorantisocial behaviorinterventionneuroendocrinology

Identifiers

PMID24681586
PMCPMC4278576

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.