ReviewHormones and behavior2014
On the value of seasonal mammals for identifying mechanisms underlying the control of food intake and body weight.
Review in Hormones and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impacts of climate change on childhood obesity: an updated systematic literature review.BMJ open · 2025Pooled it
- Polyphenism Through RNA Chemical Modifications.Molecular ecology · 2026Review
- Sex impact on daily activity and physiological, metabolic and hormonal responses to different photoperiod regimens in diet-induced obese fischer 344 rats.Journal of physiology and biochemistry · 2025Article
- Prolactin Regulates Seasonal Changes in Renal Rheostasis in Djungarian Hamsters.Endocrinology · 2025Article
- Tanycytes from a bird's eye view: gene expression profiling of the tanycytic region under different seasonal states in the Svalbard ptarmigan.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025Article
- Grape-Seed Proanthocyanidins Modulate Adipose Tissue Adaptations to Obesity in a Photoperiod-Dependent Manner in Fischer 344 Rats.Nutrients · 2023Article
- Day-night and seasonal variation of human gene expression across tissues.PLoS biology · 2023Article
- Photoperiodic Remodeling of Adiposity and Energy Metabolism in Non-Human Mammals.International journal of molecular sciences · 2023Review
- The Effect of Leptin on the Blood Hormonal Profile (Cortisol, Insulin, Thyroid Hormones) of the Ewe in Acute Inflammation in Two Different Photoperiodical Conditions.International journal of molecular sciences · 2022Article
- Day-night and seasonal variation of human gene expression across tissues.bioRxiv : the preprint server for biology · 2022Article
- Beneficial Effects of Early Time-Restricted Feeding on Metabolic Diseases: Importance of Aligning Food Habits with the Circadian Clock.Nutrients · 2021Review
- Seasonal changes in adenosine kinase in tanycytes of the Arctic ground squirrel (Urocitellus parryii).Journal of chemical neuroanatomy · 2021Article
- Polymorphism of winter phenotype in Siberian hamster: consecutive litters do not differ in photoresponsiveness but prolonged acclimation to long photoperiod inhibits winter molt.Frontiers in zoology · 2021Article
- Regional Differences in Height, Weight, and Body Composition may Result from Photoperiodic Responses: An Ecological Analysis of Japanese Children and Adolescents.Journal of circadian rhythms · 2021Article
- Physiological mechanisms underlying children's circannual growth patterns and their contributions to the obesity epidemic in elementary school age children.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020Review
- Transcriptomic analysis of immune response to bacterial lipopolysaccharide in zebra finch (Taeniopygia guttata).BMC genomics · 2019Article
- Genome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify mechanisms for seasonal energy balance.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Day length may make geographical difference in body size and proportions: An ecological analysis of Japanese children and adolescents.PloS one · 2019Article
- Chemerin: a multifaceted adipokine involved in metabolic disorders.The Journal of endocrinology · 2018Review
- The Value of Comparative Animal Research: Krogh's Principle Facilitates Scientific Discoveries.Policy insights from the behavioral and brain sciences · 2018Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
This article is part of a Special Issue "Energy Balance". Seasonal cycles of adiposity and body weight reflecting changes in both food intake and energy expenditure are the norm in mammals that have evolved in temperate and polar habitats. Innate circannual rhythmicity and direct responses to the annual change in photoperiod combine to ensure that behavior and energy metabolism are regulated in anticipation of altered energetic demands such as the energetically costly processes of hibernation, migration, and lactation. In the last decade, major progress has been made into identifying the central mechanisms that underlie these profound long-term changes in behavior and physiology. Surprisingly they are distinct from the peptidergic and aminergic systems in the hypothalamus that have been identified in studies of the laboratory mouse and rat and implicated in timing meal intervals and in short-term responses to caloric restriction. Comparative studies across rodents, ungulates and birds reveal that tanycytes embedded in the ependymal layer of the third ventricle play a critical role in seasonal changes because they regulate the local availability of thyroid hormone. Understanding how this altered hormonal environment might regulate neurogenesis and plasticity in the hypothalamus should provide new insight into development of strategies to manage appetite and body weight.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.