Evidence map›Paper›PMID 24680829›Full record

ArticleAutonomic neuroscience : basic & clinical2014

Mechanical and metabolic reflex activation of the sympathetic nervous system in younger adults with metabolic syndrome.

Jacqueline Limberg, Barbara Morgan, William Schrage

Abstract read
In one paragraph

Article in Autonomic neuroscience : basic & clinical, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Effect of Metaboreflex on Cardiovascular System in Subjects of Metabolic Syndrome.Journal of clinical and diagnostic research : JCDR · 2017
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jacqueline LimbergDepartment of Kinesiology, School of Education, University of Wisconsin - Madison, Madison, WI 53706, United States. Electronic address: limberg.jacqueline@mayo.edu.
Barbara MorganDepartment of Orthopedics and Rehabilitation, School of Medicine and Public Health, University of Wisconsin - Madison, Madison, WI 53706, United States.
William SchrageDepartment of Kinesiology, School of Education, University of Wisconsin - Madison, Madison, WI 53706, United States.
University of Wisconsin–Madison · US

Funding

ZOLEDRONATE PREVENTS BONE LOSS IN OVARIECTOMIZED RHESUS MONKEYSP51RR000167 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI WATKINS, DAVID I · 1985 to 2011
$106.7M
Peripheral Vasodilation in Obese HumansR01HL105820 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI SCHRAGE, WILLIAM G · 2011 to 2015
$2.7M
NCRR NIH HHS P51 RR000167NCRR NIH HHS RR000167NHLBI NIH HHS HL105820NHLBI NIH HHS R01 HL105820
6 · The paper itself

Abstract

aimBased on reports of exaggerated blood pressure responses to whole-body exercise in patients with metabolic syndrome (MetSyn), we tested the hypothesis that MetSyn adults would exhibit augmented sympathetic and pressor responses to mechanoreflex and metaboreflex activation when compared with healthy, age-matched control subjects.

methodsWe studied 12 adults with MetSyn (34±3years) and 12 healthy control subjects (34±3years). Heart rate (HR; ECG), blood pressure (BP; finger photoplethysmography), and MSNA (microneurography of the peroneal nerve) were measured during: (1) static handgrip exercise at 15% of maximal voluntary contraction (MVC), and (2) static handgrip exercise at 30% MVC to fatigue, followed by post-exercise ischemia (PEI). Increases in MSNA, HR, and BP were assessed.

resultsDuring static exercise at both 15 and 30% MVC, increases in MSNA, HR, and BP were not different between groups. MSNA remained significantly elevated from baseline during PEI and responses were not different between groups.

conclusionSympathetic and pressor responses to mechanoreflex and metaboreflex activation are not augmented in younger adults with MetSyn.

Indexed as

AdultBlood PressureExerciseFemaleForearmHand StrengthHeart RateHumansIschemiaMaleMetabolic SyndromeMuscle ContractionMuscle FatigueMuscle, SkeletalReflexBlood pressureExercise pressor reflexMSNAObesityStatic exercise

Identifiers

PMID24680829
PMCPMC4058385
OpenAlexW2017449202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.