ArticleParasitology2014
Comparing parasitological vs serological determination of Schistosoma haematobium infection prevalence in preschool and primary school-aged children: implications for control programmes.
Article in Parasitology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01424410 (Health Benefits of Repeated Treatment in Pediatric Schistosomiasis), which is not on this map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Health Benefits of Repeated Treatment in Pediatric Schistosomiasis
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic accuracy of rapid and point-of-care tests forFrontiers in parasitology · 2026Pooled it
- A Mini-Review on Elisa-Based Diagnosis of Schistosomiasis.Current molecular medicine · 2024Pooled it
- Efficacy and safety of single-dose 40 mg/kg oral praziquantel in the treatment of schistosomiasis in preschool-age versus school-age children: An individual participant data meta-analysis.PLoS neglected tropical diseases · 2020Pooled it
- Comparative Assessment of Health Benefits of Praziquantel Treatment of Urogenital Schistosomiasis in Preschool and Primary School-Aged Children.BioMed research international · 2016Trial
- Identification of a circulating carbohydrate antigen as a highly specific and sensitive target for schistosomiasis serology.Journal of clinical microbiology · 2025Article
- National Consensus on Introducing and Delivery of Paediatric Praziquantel for Curative and Preventive Treatment of Schistosomiasis Among Pre-school Children in Tanzania.The East African health research journal · 2025Article
- Schistosomiasis in migrant children and adolescents in a paediatric tropical referral unit in Spain: diagnosis and long-term management challenges.European journal of pediatrics · 2024Article
- Expression of CD117 (c-Kit) on Circulating B Cells in Pediatric Schistosomiasis.Infection and immunity · 2022Article
- Potential Utility of Systemic Plasma Biomarkers for Evaluation of Pediatric Schistosomiasis in Western Kenya.Frontiers in immunology · 2022Article
- Algorithm for diagnosis of early Schistosoma haematobium using prodromal signs and symptoms in pre-school age children in an endemic district in Zimbabwe.PLoS neglected tropical diseases · 2021Article
- Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children.PLoS neglected tropical diseases · 2020Article
- Association of Schistosoma haematobium infection morbidity and severity on co-infections in pre-school age children living in a rural endemic area in Zimbabwe.BMC public health · 2020Article
- Article
- Knowledge, perceptions and practices regarding schistosomiasis among women living in a highly endemic rural district in Zimbabwe: implications on infections among preschool-aged children.Parasites & vectors · 2019Article
- Urogenital schistosomiasis and risk factors of infection in mothers and preschool children in an endemic district in Zimbabwe.Parasites & vectors · 2019Article
- Reinfection of urogenital schistosomiasis in pre-school children in a highly endemic district in Northern Zimbabwe: a 12 months compliance study.Infectious diseases of poverty · 2018Article
- Comparison of ELISA and Urine Microscopy for Diagnosis ofJournal of Korean medical science · 2018Article
- Paediatric schistosomiasis: What we know and what we need to know.PLoS neglected tropical diseases · 2018Review
- Dynamics of paediatric urogenital schistosome infection, morbidity and treatment: a longitudinal study among preschool children in Zimbabwe.BMJ global health · 2018Article
- Identifying and evaluating field indicators of urogenital schistosomiasis-related morbidity in preschool-aged children.PLoS neglected tropical diseases · 2015Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
To combat schistosomiasis, the World Health Organization (WHO) recommends that infection levels are determined prior to designing and implementing control programmes, as the treatment regimens depend on the population infection prevalence. However, the sensitivity of the parasitological infection diagnostic method is less reliable when infection levels are low. The aim of this study was to compare levels of Schistosoma haematobium infection obtained by the parasitological method vs serological technique. Infection levels in preschool and primary school-aged children and their implications for control programmes were also investigated. Infection prevalence based on serology was significantly higher compared with that based on parasitology for both age groups. The difference between infection levels obtained using the two methods increased with age. Consequentially, in line with the WHO guidelines, the serological method suggested a more frequent treatment regimen for this population compared with that implied by the parasitological method. These findings highlighted the presence of infection in children aged ⩽5 years, further reiterating the need for their inclusion in control programmes. Furthermore, this study demonstrated the importance of using sensitive diagnostic methods as this has implications on the required intervention controls for the population.
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