ArticleBMC infectious diseases2014
Antimicrobial susceptibility patterns of Ureaplasma species and Mycoplasma hominis in pregnant women.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global analysis on the mutations associated with multidrug-resistant urogenital mycoplasmas and ureaplasmas infection: a systematic review and meta-analysis.Annals of clinical microbiology and antimicrobials · 2023Pooled it
- Adverse pregnancy and birth outcomes associated withBMJ open · 2022Pooled it
- Isolation, prevalence, and antimicrobial resistance profiles of Ureaplasma spp. and Mycoplasma hominis in cervical secretions from pregnant and postpartum women in Hangzhou, China.BMC pregnancy and childbirth · 2026Article
- Comparative analysis of diagnostic kits for detectingPractical laboratory medicine · 2026Article
- Diagnostic challenges in postoperative pelvic infections associated withFrontiers in cellular and infection microbiology · 2026Article
- Prevalence ofEpidemiology and infection · 2025Article
- Changes in vaginal Ureaplasma and Lactobacillus due to antibiotic regimen for premature rupture of membranes.PloS one · 2025Article
- Article
- Epidemiological characteristics and clinical antibiotic resistance analysis of Ureaplasma urealyticum infection among women and children in southwest China.BMC infectious diseases · 2024Article
- Article
- Case Report: Double trouble: a rare case of successfully treatedFrontiers in cellular and infection microbiology · 2023Article
- The prevalence of Mycoplasma hominis in Outpatients at a Tertiary Care Hospital in East India.Cureus · 2022Article
- Phenotypic Antimicrobial Susceptibility and Genotypic Characterization of ClinicalFrontiers in microbiology · 2021Article
- Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes.American journal of obstetrics and gynecology · 2020Article
- Antimicrobial Resistance in ClinicalAntimicrobial agents and chemotherapy · 2020Article
- Spread of multidrug resistance amongAntimicrobial resistance and infection control · 2020Article
- An Observational Study: IsThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020Article
- Roles ofThe world journal of men's health · 2019Article
- Prevalence of genital Mycoplasma and response to eradication treatment in patients undergoing assisted reproductive techniques.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019Article
- Successful Whole Genome Sequencing-guided Treatment of Mycoplasma hominis Ventriculitis in a Preterm Infant.The Pediatric infectious disease journal · 2019Article
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundGenital mycoplasmas colonise up to 80% of sexually mature women and may invade the amniotic cavity during pregnancy and cause complications. Tetracyclines and fluoroquinolones are contraindicated in pregnancy and erythromycin is often used to treat patients. However, increasing resistance to common antimicrobial agents is widely reported. The purpose of this study was to investigate antimicrobial susceptibility patterns of genital mycoplasmas in pregnant women.
methodsSelf-collected vaginal swabs were obtained from 96 pregnant women attending an antenatal clinic in Gauteng, South Africa. Specimens were screened with the Mycofast Revolution assay for the presence of Ureaplasma species and Mycoplasma hominis. The antimicrobial susceptibility to levofloxacin, moxifloxacin, erythromycin, clindamycin and tetracycline were determined at various breakpoints. A multiplex polymerase chain reaction assay was used to speciate Ureaplasma positive specimens as either U. parvum or U. urealyticum.
resultsSeventy-six percent (73/96) of specimens contained Ureaplasma spp., while 39.7% (29/73) of Ureaplasma positive specimens were also positive for M. hominis. Susceptibilities of Ureaplasma spp. to levofloxacin and moxifloxacin were 59% (26/44) and 98% (43/44) respectively. Mixed isolates (Ureaplasma species and M. hominis) were highly resistant to erythromycin and tetracycline (both 97% resistance). Resistance of Ureaplasma spp. to erythromycin was 80% (35/44) and tetracycline resistance was detected in 73% (32/44) of Ureaplasma spp. Speciation indicated that U. parvum was the predominant Ureaplasma spp. conferring antimicrobial resistance.
conclusionsTreatment options for genital mycoplasma infections are becoming limited. More elaborative studies are needed to elucidate the diverse antimicrobial susceptibility patterns found in this study when compared to similar studies. To prevent complications in pregnant women, the foetus and the neonate, routine screening for the presence of genital mycoplasmas is recommended. In addition, it is recommended that antimicrobial susceptibility patterns are determined.
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