ArticleNorth American journal of medical sciences2014
Evaluation of regression in autism spectrum disorder based on parental reports.
Article in North American journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Enigma of autism regression mechanistic pathways, clinical phenotypes, and early intervention implications.World journal of clinical pediatrics · 2026Review
- Exploration of Risk Factors for Language Regression According to Parent Reports in Turkish Children with Autism Spectrum Disorder.Psychiatry and clinical psychopharmacology · 2024Article
- Shedding light on biological sex differences and microbiota-gut-brain axis: a comprehensive review of its roles in neuropsychiatric disorders.Biology of sex differences · 2022Review
- Analysis of Global and Local DNA Methylation Patterns in Blood Samples of Patients With Autism Spectrum Disorder.Frontiers in pediatrics · 2021Article
- Inflammatory Biomarkers are Correlated with Some Forms of Regressive Autism Spectrum Disorder.Brain sciences · 2019Article
- Changing conceptualizations of regression: What prospective studies reveal about the onset of autism spectrum disorder.Neuroscience and biobehavioral reviews · 2019Review
- Autism Spectrum Disorder (ASD) with and without Mental Regression is Associated with Changes in the Fecal Microbiota.Nutrients · 2019Article
- Is Autism Inborn And Lifelong For Everyone?Neuropsychiatric disease and treatment · 2019Article
- Onset patterns in autism: Variation across informants, methods, and timing.Autism research : official journal of the International Society for Autism Research · 2018Article
- Children With Autism Spectrum Disorder With Regression Exhibit a Different Profile in Plasma Cytokines and Adhesion Molecules Compared to Children Without Such Regression.Frontiers in pediatrics · 2018Article
- Specific Medical Conditions Are Associated with Unique Behavioral Profiles in Autism Spectrum Disorders.Frontiers in neuroscience · 2016Article
- Relevance of Neuroinflammation and Encephalitis in Autism.Frontiers in cellular neuroscience · 2015Review
- A Prospective Longitudinal Assessment of Medical Records for Diagnostic Substitution among Subjects Diagnosed with a Pervasive Developmental Disorder in the United States.Frontiers in pediatrics · 2015Article
- The pivotal role of parents in documenting early development.North American journal of medical sciences · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResearch indicates that some children with autism spectrum disorder (ASD) experience a developmental regression.
aimsThe study examined the percentage of children with autism, pervasive developmental disorder (PDD), ASD, and Asperger syndrome (AS) who were considered to be delayed (D), regressed (R), or delayed and later regressed (DR) and examined any relationship with autism severity, time of onset, factors associated with onset, gastrointestinal (GI) symptoms, race, age, and gender. MATERIALS AND
methodsThe study reviewed developmental and medical information based on parental reports of 135 children with a diagnosis of autism, PDD, ASD, or AS.
resultsThe number of children in the D group was 53 (39.2%) with 19 (14.1%) in the DR group and 63 (46.7%) in the R group. Thus, 82 children (60.7%) were reported to have R. In regard to onset of symptoms, there was a significant difference between the D and R groups as well as between the DR and R groups. The analyses showed that there was no significant relationship between age, gender, race, severity, or GI symptoms and membership in any group; D, DR, or R. The majority of parents reported that the regression was preceded by or was associated with vaccinations (57.3%) or another medically related event (11.0%).
conclusionsThe findings are consistent with previous research and reinforce our understanding of regression in those children with an ASD diagnosis.
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