Evidence map›Paper›PMID 24678438›Full record

ArticleJournal of clinical imaging science2014

Two Cases of Spinal, Extraosseous, Intradural Ewing's sarcoma/Peripheral Neuroectodermal Tumor: Radiologic, Pathologic, and Molecular Analysis.

Stacey K Mardekian, Ashish Gandhe, Markku Miettinen, Svetlana Pack, Mark T Curtis, Ziedulla Abdullaev

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical imaging science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Intradural extraosseous Ewing sarcoma.Skeletal radiology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Giant Calvarial Ewing's Sarcoma: A Case Report.Journal of neurological surgery reports · 2018
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Stacey K MardekianDepartment of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
Ashish GandheDepartment of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
Markku MiettinenDepartment of Laboratory of Pathology, National Cancer Institute, United States.
Svetlana PackDepartment of Laboratory of Pathology, National Cancer Institute, United States.
Mark T CurtisDepartment of Pathology, Thomas Jefferson University Hospital, Philadelphia, PA, United States.
Ziedulla AbdullaevDepartment of Laboratory of Pathology, National Cancer Institute, United States.
Thomas Jefferson University Hospital · USNational Cancer Institute · MYNational Cancer Institute · US

Funding

Genreal Surgical PathologyZIDBC011291 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MIETTINEN, MARKKU · 2010 to 2025
$30.3M
Development of FISH Molecular Diagnostics to support Clinical Trials at NCIZIDBC011349 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PACK, SVETLANA · 2010 to 2014
$2.7M
6 · The paper itself

Abstract

Extraosseous Ewing's sarcoma/peripheral neuroectodermal tumors (ES/PNETs) are rare neoplasms that account for approximately 10%-15% of soft tissue sarcomas in children and 5% of soft tissue sarcomas in adults. Primary spinal, extraosseous, intradural ES/PNETs are even less common. The diagnosis of ES/PNET is extremely challenging, because the tumor can have a nonspecific radiologic appearance, and the histologic features are shared by many other "small round cell tumors." Thus, ES/PNET should be included in the radiologic and pathologic differential diagnosis, even in older patients and in unusual tumor sites. We report two cases of spinal, extraosseous, intradural ES/PNETs in adults who presented with back pain. Magnetic resonance imaging revealed contrast enhancing, intradural lesions in the area of the conus medullaris. The tumor in Case 1 was partially intramedullary, while the tumor in Case 2 was exclusively extramedullary. In both cases, the radiologic and intraoperative surgical impression favored ependymoma. The diagnosis of ES/PNET was established in both cases by histopathologic, immunohistochemical, and molecular analysis.

Indexed as

Ewing sarcoma/peripheral neuroectodermal tumorintradural spinal neoplasmsperipheral neuroectodermal tumors

Identifiers

PMID24678438
PMCPMC3952377
OpenAlexW1999022383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.