ArticleJournal of natural science, biology, and medicine2014
Study of extended spectrum β-lactamase producing Enterobacteriaceae and antibiotic coresistance in a tertiary care teaching hospital.
Article in Journal of natural science, biology, and medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Molecular insights, resistance profiling, and in silico structural modeling of extended-spectrum beta-lactamase-producing E. coli in camels.Veterinary research communications · 2026Article
- Antibiotic resistance profiles and co-occurrence of ESBL and AmpC β-lactamase genes in ESBL-producing Gram-negative bacteria of clinical origin.BMC microbiology · 2026Article
- Emerging Trends of Beta-Lactamases in Western Nepal: A Growing Public Health Concern.International journal of microbiology · 2025Article
- Recent Bacteriological Trends and Emerging Antimicrobial Resistance among Hospitalized Patients in a Tertiary Care Center, Central India.Journal of pharmacy & bioallied sciences · 2024Article
- Fecal carriage of extended-spectrum β-lactamase-producing enterobacterales from hospitals and community settings in Gaza Strip, Palestine.BMC microbiology · 2023Article
- Article
- Phenotypic and genotypic antibiotic susceptibility profiles of Gram-negative bacteria isolated from bloodstream infections at a referral hospital, Lusaka, Zambia.PLOS global public health · 2023Article
- Magnitude and Molecular Characterization of Extended-Spectrum β-Lactamase Genes among Klebsiella pneumoniae Isolates in a Large Tertiary Hospital in Ethiopia.Advances in experimental medicine and biology · 2023Article
- Efficacy andFrontiers in cellular and infection microbiology · 2022Review
- Occurrence and distribution of extended-spectrum β-lactamase in clinicalGhana medical journal · 2021Article
- Carriage Prevalence of Extended-Spectrum β-Lactamase Producing Enterobacterales in Outpatients Attending Community Health Centers in Blantyre, Malawi.Tropical medicine and infectious disease · 2021Article
- Prevalence of CTX-MBioMed research international · 2021Article
- Characterisation of ESKAPE Pathogens with Special Reference to Multidrug Resistance and Biofilm Production in a Nepalese Hospital.Infection and drug resistance · 2021Article
- Article
- Detection of VIM-1, VIM-2 and IMP-1 metallo- β-lactamase genes inIranian journal of microbiology · 2019Article
- Article
- Extended-spectrum beta-lactamase production and multi-drug resistance amongAntimicrobial resistance and infection control · 2019Article
- Extended spectrum beta-lactamase and metallo beta-lactamase production among Escherichia coli and Klebsiella pneumoniae isolated from different clinical samples in a tertiary care hospital in Kathmandu, Nepal.Annals of clinical microbiology and antimicrobials · 2017Article
- Bacteriological profile and antibiotic susceptibility patterns of clinical isolates in a tertiary care cancer center.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric OncologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo study the prevalence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae and coresistance to other commonly used antibiotics from the Bhopal region of Central India. SETTINGS AND
designA prospective study was conducted from September 2011 to August 2012 in Microbiology Department of our tertiary health care center. MATERIALS AND
methodsA total of 1044 Enterobacteriaceae isolates were recovered from various specimens. ESBL production was detected by using Clinical Laboratory Standard Institute (CLSI) that described the phenotypic confirmatory test along with routine antibiotic susceptibility testing. STATISTICAL ANALYSIS: Two-tailed Z-test.
resultsEscherichia coli was the most common isolate (65.32%). ESBL production was confirmed in 504 (48.27%) isolates. The isolates of E. coli (50.14%) were the most common ESBL producers. Maximum ESBL isolates were obtained from urine samples (52.28%) and male patients (52.54%). Sensitivity to imipenem was 100% followed by piperacillin-tazobactam (89.28%), meropenem (87.5%), and amikacin (83.92%). Significant resistance was detected against trimethoprim-sulfomethoxazole, fluoroquinolones, and gentamicin.
conclusionThis is the only study conducted from Central India and shows high prevalence of ESBL production among Enterobacteriaceae. Imipenem seems to be more sensitive than meropenem. Piperacillin-tazobactam combination was found to be the best among the β-lactam-β-lactamase inhibitor combinations. Prevalence of ESBL producers were more in males than females.
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