Evidence map›Paper›PMID 24678170›Full record

ArticleAsian journal of transfusion science2014

Hepatitis E seroprevalence among blood donors: A pilot study from Western India.

Maitrey D Gajjar, Nidhi M Bhatnagar, Rajesh V Sonani, Shweta Gupta, Tarak Patel

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asian journal of transfusion science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Transfusion-transmitted hepatitis E: What we know so far?World journal of gastroenterology · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Hepatitis E: an old infection with new implications.Blood transfusion = Trasfusione del sangue · 2015
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maitrey D GajjarDepartment of Immunohaematology and Blood Transfusion, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
Nidhi M BhatnagarDepartment of Immunohaematology and Blood Transfusion, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
Rajesh V SonaniDepartment of Immunohaematology and Blood Transfusion, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
Shweta GuptaDepartment of Immunohaematology and Blood Transfusion, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
Tarak PatelDepartment of Immunohaematology and Blood Transfusion, B. J. Medical College and Civil Hospital, Ahmedabad, Gujarat, India.
B.J. Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis E virus (HEV) is emerging as a potential threat to blood safety after several cases of transmission by transfusion or transplantation have been described. Currently, blood donors in India are not screened for HEV. The studies conducted on HEV in recent times in India have focused on epidemiology and future perspectives, but there is no published study on blood donors. To address possible issues surrounding blood safety and risk of HEV transmission within the Indian blood supply, HEV seroprevalence study was conducted in blood donors at our center. MATERIALS AND

methodsA total of 460 male voluntary blood donors were selected for the study and after taking their written consent. Serum anti-HEV IgM was detected by Dia.Pro HEV kit (Diagnostic Bioprobes Srl, Milano, Italy).

resultsThe study population was composed of 460 male voluntary blood donors and their age ranged from 18 to 60 years with a mean age of 30.48 years. Out of 460 donors, 22 (4.78%) donors were tested positive for IgM anti-HEV and the mean value alanine aminotransferase (ALT) was 26.06 IU/L, the highest being 93.5 IU/L. Normal reference value of ALT in our center was 40 IU/L. Out of 22 anti-HEV positive donors, 19 (86.36%) had ALT values above 40 IU/L.

conclusionHEV seroprevalence of 4.78% in our center. Though reports of HEV transmission through blood has been reported from various parts of the world, before making it as a mandatory screening test among blood donors in India, further studies with confirmatory assay of HEV need to be done.

Indexed as

Blood donorshepatitis E virusseroprevalence

Identifiers

PMID24678170
PMCPMC3943141
OpenAlexW2013262635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.