Evidence map›Paper›PMID 24677528›Full record

ArticleChembiochem : a European journal of chemical biology2014

A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis.

Jianjun Zhang, Shanteri Singh, Ryan R Hughes, Maoquan Zhou, Manjula Sunkara, Andrew J Morris, Jon S Thorson

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Exploring the NucleophilicJournal of microbiology and biotechnology · 2020
    Article
  5. Article
  6. OleD Loki as a Catalyst for Hydroxamate Glycosylation.Chembiochem : a European journal of chemical biology · 2020
    Article
  7. OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.Chembiochem : a European journal of chemical biology · 2017
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianjun Zhang
Shanteri Singh
Ryan R Hughes
Maoquan Zhou
Manjula Sunkara
Andrew J Morris
Jon S Thorson

Funding

The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2012 to 2017
$13.7M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
In Vitro Glycorandomization of Natural ProductsR37AI052218 · NIAID · UNIVERSITY OF KENTUCKY · PI THORSON, JON SCOTT · 2012 to 2021
$4.0M
Thermo/Finnigan TSQ AM Triple Stage Quadrupole Mass SpectrometerS10RR024598 · NCRR · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2008 to 2008
$493k
Advion Triversa Nanomate/ABSciex Nanospray III Ion Source for Targeted LipidomicsS10RR026884 · NCRR · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2011 to 2011
$106k
NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1TR000117NCRR NIH HHS S10 RR024598NCRR NIH HHS S10 RR026884NIAID NIH HHS R37 AI052218NIAID NIH HHS R37 AI52218NIGMS NIH HHS P20 GM103527
6 · The paper itself

Abstract

A set of 2-chloro-4-nitrophenyl glucosamino-/xylosaminosides were synthesized and assessed as potential substrates in the context of glycosyltransferase-catalyzed formation of the corresponding UDP/TDP-α-D-glucosamino-/xylosaminosugars and in single-vessel model transglycosylation reactions. This study highlights a robust platform for aminosugar nucleotide synthesis and reveals OleD Loki to be a proficient catalyst for U/TDP-aminosugar synthesis and utilization

Indexed as

Carbohydrate MetabolismAminesCarbohydratesCatalysisGlucosidesGlycosyltransferasesNitrophenolsNucleotidesProtein EngineeringStreptomyces antibioticusSubstrate Specificity4-nitrophenylAminesCarbohydratesGlucosidesGlycosyltransferasesNitrophenolsNucleotides

Identifiers

PMID24677528
PMCPMC4051237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.