ArticleBiologics in therapy2014
Weekly Teriparatide for Delayed Unions of Atypical Subtrochanteric Femur Fractures.
Article in Biologics in therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Medical Management of Patients After Atypical Femur Fractures: a Systematic Review and Recommendations From the European Calcified Tissue Society.The Journal of clinical endocrinology and metabolism · 2020Guideline
- The role of peptides in bone healing and regeneration: a systematic review.BMC medicine · 2016Pooled it
- Fracture healing on non-union fracture model promoted by non-thermal atmospheric-pressure plasma.PloS one · 2024Article
- Biological aspects to enhance fracture healing.EFORT open reviews · 2023Review
- Efficacy and Safety of Teriparatide in Improving Fracture Healing and Callus Formation: A Systematic Review.Cureus · 2023Review
- A brief review and clinical evidences of teriparatide therapy for atypical femoral fractures associated with long-term bisphosphonate treatment.Frontiers in surgery · 2022Review
- Successful treatment of infectious delayed union after ulnar shortening osteotomy using once-weekly teriparatide with low-intensity pulsed ultrasound.Case reports in plastic surgery & hand surgery · 2021Article
- Scope and Limits of Teriparatide Use in Delayed and Nonunions: A Case Series.Clinics and practice · 2021Article
- Article
- Teriparatide for treating delayed union and nonunion: A systematic review.Journal of clinical orthopaedics and trauma · 2020Review
- Surgical outcome of atypical subtrochanteric and femoral fracture related to bisphosphonates use in osteoporotic patients with or without teriparatide treatment.BMC musculoskeletal disorders · 2017Article
- Osteoporosis: a discussion on the past 5 years.Current reviews in musculoskeletal medicine · 2017Review
- Long-term use of bisphosphonates in osteoporosis.Saudi medical journal · 2017Article
- Atypical Femur Fractures in Patients Treated with Bisphosphonates: Identification, Management, and Prevention.Rambam Maimonides medical journal · 2016Review
- Short-term effects of teriparatide versus placebo on bone biomarkers, structure, and fracture healing in women with lower-extremity stress fractures: A pilot study.Journal of clinical & translational endocrinology · 2016Article
- Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016Review
- Effect of Teriparatide on Healing of Atypical Femoral Fractures: A Systemic Review.Journal of bone metabolism · 2015Review
- Effective treatment of delayed union of a lumbar vertebral fracture with daily administration of teriparatide in a patient with diffuse idiopathic skeletal hyperostosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe occurrence of atypical femur fractures (AFFs) in patients on prolonged bisphosphonate treatment has been gaining medical attention, but the use of pharmacotherapy for these fractures has not been explored in detail. The authors describe a case of AFFs successfully treated with once-weekly administration of 56.5 μg teriparatide (TPTD). CASE PRESENTATION: The patient was a 74-year-old female patient who had been taking alendronate for approximately 6 years and who suffered with a fall while walking. X-rays revealed a subtrochanteric right femur fracture. The contralateral femur showed cortical thickening and a transverse radiolucent fracture line. Based on these specific features, the patient was diagnosed with AFF. The patient underwent osteosynthesis with intramedullary nailing for the right fracture. Alendronate treatment was discontinued. Low-intensity pulsed ultrasonography therapy did not affect the healing of the fracture with delayed union, even after 3 months of application. Prophylactic osteosynthesis was performed for the subtrochanteric left femur. Bone tissue collected from the left fracture site during surgery showed severe suppression of bone turnover. Union of bilateral femurs was achieved after 3 months of a once-weekly administration of TPTD.
conclusionOnce-weekly TPTD treatment is shown to be beneficial for improving the healing of AFFs showing delayed union.
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