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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014

Danish population-based reference data for the EORTC QLQ-C30: associations with gender, age and morbidity.

Therese Juul, Morten Aagaard Petersen, Bernhard Holzner, Søren Laurberg, Peter Christensen, Mogens Grønvold

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

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  10. Trajectory of quality of life among patients with cancer at the end of life: a longitudinal survey study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  20. Assessment of Quality of Life in Patients with Colorectal Cancer in Kazakhstan.Asian Pacific journal of cancer prevention : APJCP · 2023
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Therese JuulSection for Colorectal and Mamma-Endocrine Surgery, Department of Surgery, Aarhus University Hospital, Aarhus, Denmark, therjuul@rm.dk.
Morten Aagaard Petersen
Bernhard Holzner
Søren Laurberg
Peter Christensen
Mogens Grønvold

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeGeneral population reference data are useful in the interpretation of health-related quality of life (HRQoL) results, but for the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30 (EORTC QLQ-C30), such data have been published for only seven countries. In 1992, Danish general population data were collected from women only for EORTC QLQ-C30 version 1. Since no Danish reference data exists for men and women for the QLQ-C30 version 3.0, the aims of this study were to generate such data and to investigate the associations between EORTC QLQ-C30 outcomes and age, gender and morbidity, as well as trends over time.

methodsAn age- and gender-stratified random sample of 3,080 Danes was drawn from the Danish Civil Registration System. The EORTC QLQ-C30 was administered electronically and by mail along with a short questionnaire concerning socio-demographics/morbidity.

resultsResponses were obtained from 1,832 individuals (60.1% of 3,009 eligible individuals). Response rates varied across age groups, ranging from 41.9% (20-29 years) to 76.1% (70-79 years). The majority of subscales were strongly associated with age and morbidity. Between genders only small, but clinically meaningful and statistically significant differences were found in five out of fifteen scales. When comparing Danish women 20 years ago and today, a tendency toward slightly improved function/reduced symptoms was observed, but the differences were small and statistically significant in only three subscales.

conclusionThis study is the first to present Danish general population reference values for the EORTC QLQ-C30 version 3.0. Age and morbidity are important potential confounders that must be taken into account in HRQoL studies.

Indexed as

AdultAgedAged, 80 and overAge FactorsDenmarkFemaleHealth Status IndicatorsHumansMaleMiddle AgedMorbidityNeoplasmsPsychometricsQuality of LifeReference ValuesSurveys and Questionnaires

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.