ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2014
The impact of common co-morbidities (as measured using the Charlson index) on hip fracture risk in elderly men: a population-based cohort study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers, 3 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 70 citations in OpenAlex.
- Pooled it
- Effect of Cigarette Smoking on Risk of Hip Fracture in Men: A Meta-Analysis of 14 Prospective Cohort Studies.PloS one · 2016Pooled it
- Peripheral arterial disease and risk of hip fracture: A systematic review and meta-analysis of cohort studies.Journal of postgraduate medicinePooled it
- Predisposing factors for contralateral hip fractures in elderly patients over 80 years old.Joint diseases and related surgery · 2026Article
- Use of Potentially Inappropriate Medication and Association with Falls During Hospitalisation: An Analysis Based on Electronic Health Records (POLAR_MI project).Drugs - real world outcomes · 2026Article
- Impact of dementia and mild cognitive impairment on bone health in older people.Aging clinical and experimental research · 2024Review
- A Higher Charlson Comorbidity Index Is a Risk Factor for Hip Fracture in Older Adults During Low-Temperature Periods: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2024Article
- The medication-based Rx-Risk Comorbidity Index and risk of hip fracture - a nationwide NOREPOS cohort study.BMC medicine · 2024Article
- Impact of nurse-led interprofessional work in older patients with heart failure and multimorbidity: A retrospective cohort study.American heart journal plus : cardiology research and practice · 2024Article
- The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Observational
- Risk factors for second hip fracture in elderly patients: an age, sex, and fracture type matched case-control study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- Epidemiology of major osteoporotic fractures: a population-based analysis in Catalonia, Spain.Archives of osteoporosis · 2022Article
- Evaluating the performance of the Charlson Comorbidity Index (CCI) in fracture risk prediction and developing a new Charlson Fracture Index (CFI): a register-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Health care utilization and excess costs after pelvic fractures among older people in Germany.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Observational
- Proximal humeral fracture in patients with high Charlson comorbidity index: mortality rate according to treatment choice.Musculoskeletal surgery · 2021Article
- Systematic Review: Are the Elderly With Diabetes Mellitus Type 2 Prone to Fragility Fractures?Cureus · 2021Review
- Predicting Severe/Critical Outcomes in Patients With SARS-CoV2 Pneumonia: Development of the prediCtion seveRe/crItical ouTcome in COVID-19 (CRITIC) Model.Frontiers in medicine · 2021Article
- Association between statin use and osteoporotic fracture in patients with chronic obstructive pulmonary disease: a population-based, matched case-control study.Lipids in health and disease · 2020Article
- Chronic Obstructive Pulmonary Disease and Incidence of Hip Fracture: A Nested Case-Control Study in the EpiChron Cohort.International journal of chronic obstructive pulmonary disease · 2020Observational
- Individual Antidepressants and the Risk of Fractures in Older Adults: A New User Active Comparator Study.Clinical epidemiology · 2020Article
Corrections and comments
- Erratum issuedMácias, J G [corrected to González-Macías, J]
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
unlabelledWe used a large population-based health care database to determine the impact of common co-morbidities on hip fracture risk amongst elderly men. We demonstrated that diabetes, chronic obstructive pulmonary disease, renal failure, HIV infection, dementia, and cerebrovascular disease are independent predictors of hip fracture, as is a Charlson score of ≥ 3.
introductionRisk factors for hip fractures in men are still unclear. We aimed to identify common co-morbidities (amongst those in the Charlson index) that confer an increased risk of hip fracture amongst elderly men.
methodsWe conducted a population-based cohort study using data from the SIDIAP (Q) database. SIDIAP(Q) contains primary care and hospital inpatient records of a representative 30% of the population of Catalonia, Spain (>2 million people). All men aged ≥ 65 years registered on 1 January 2007 were followed up until 31 December 2009. Both exposure (co-morbidities in the Charlson index) and outcome (incident hip fractures) were ascertained using ICD codes. Poisson regression models were fitted to estimate the effect of (1) each individual co-morbidity and (2) the composite Charlson index score, on hip fracture risk, after adjustment for age, body mass index, smoking, alcohol drinking, and use of oral glucocorticoids.
resultsWe observed 186,171 men for a median (inter-quartile range) of 2.99 (2.37-2.99) years. In this time, 1,718 (0.92%) participants had a hip fracture. The following co-morbidities were independently associated with hip fractures: diabetes mellitus, chronic obstructive pulmonary disease (COPD), renal failure, HIV infection, dementia, and cerebrovascular disease. A Charlson score of ≥ 3 conferred an increased hip fracture risk.
conclusionCommon co-morbidities including diabetes, COPD, cerebrovascular disease, renal failure, and HIV infection are independently associated with an increased risk of hip fracture in elderly men. A Charlson score of 3 or more is associated with a 50% higher risk of hip fracture in this population.
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