Evidence map›Paper›PMID 24676662›Full record

ArticleMemorias do Instituto Oswaldo Cruz2014

Genetic diversity and antimicrobial resistance in Streptococcus agalactiae strains recovered from female carriers in the Bucharest area.

Codruţa-Romaniţa Usein, Mădălina Militaru, Violeta Cristea, Monica Străuţ

Open access · diamondAbstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Molecular epidemiology ofMicrobial genomics · 2023
    Pooled it
  2. Zoonotic Approach toInternational journal of microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Frontiers in genetics · 2020
    Article
  7. Article
  8. High Incidence of PathogenicFrontiers in microbiology · 2018
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Codruţa-Romaniţa UseinMolecular Epidemiology Laboratory, Cantacuzino National Institute of Research/Development for Microbiology and Immunology, Bucharest, Romania.
Mădălina MilitaruMolecular Epidemiology Laboratory, Cantacuzino National Institute of Research/Development for Microbiology and Immunology, Bucharest, Romania.
Violeta CristeaSynevo Laboratories, Judetul Ilfov, Romania.
Monica StrăuţMolecular Epidemiology Laboratory, Cantacuzino National Institute of Research/Development for Microbiology and Immunology, Bucharest, Romania.
Institutul Cantacuzino · ROCarol Davila University of Medicine and Pharmacy · ROSynlab Czech (Czechia) · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the first time, we used multilocus sequence typing (MLST) to understand how Romanian group B streptococcus (GBS) strains fit into the global GBS population structure. Colonising isolates recovered from adult human females were tested for antibiotic resistance, were molecularly serotyped based on the capsular polysaccharide synthesis (cps) gene cluster and further characterised using a set of molecular markers (surface protein genes, pilus-encoded islands and mobile genetic elements inserted in the scpB-lmb intergenic region). Pulsed-field gel electrophoresis was used to complement the MLST clonal distribution pattern of selected strains. Among the 55 strains assigned to six cps types (Ia, Ib, II-V), 18 sequence types (STs) were identified by MLST. Five STs represented new entries to the MLST database. The prevalent STs were ST-1, ST-17, ST-19 and ST-28. Twenty molecular marker profiles were identified. The most common profiles (rib+GBSi1+PI-1, rib+GBSi1+PI-1, PI-2b and alp2/3+PI-1, PI-2a) were associated with the cps III/ST-17 and cps V/ST-1 strains. A cluster of fluoroquinolone-resistant strains was detected among the cps V/ST-19 members; these strains shared alp1 and IS1548 and carried PI-1, PI-2a or both. Our results support the usefulness of implementing an integrated genotyping system at the reference laboratory level to obtain the reliable data required to make comparisons between countries.

Indexed as

Genetic VariationAdultAnti-Bacterial AgentsCarrier StateDatabases, Nucleic AcidDisk Diffusion Antimicrobial TestsDNA, BacterialDNA, IntergenicDrug Resistance, MicrobialElectrophoresis, Gel, Pulsed-FieldFemaleFimbriae, BacterialGenes, BacterialHumansInterspersed Repetitive SequencesMembrane ProteinsAnti-Bacterial AgentsDNA, BacterialDNA, IntergenicMembrane Proteins

Identifiers

PMID24676662
PMCPMC4015262
OpenAlexW2163142893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.