Evidence map›Paper›PMID 24676576›Full record

ArticleJournal of applied oral science : revista FOB2014

The susceptibility of Streptococcus mutans to antibacterial photodynamic therapy: a comparison of two different photosensitizers and light sources.

Neda Hakimiha, Farzaneh Khoei, Abbas Bahador, Reza Fekrazad

Open access · diamondAbstract readEvaluation Study
In one paragraph

Article in Journal of applied oral science : revista FOB, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Neda HakimihaLaser Research Center of Dentistry, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Farzaneh KhoeiLaser Research Center of Dentistry, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Abbas BahadorMicrobiology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Reza FekrazadLaser Research Center in Medical Sciences, AJA University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRAja University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledStreptococcus mutans is the main etiological agent for dental caries. Recently, photodynamic therapy (PDT) has been introduced as a new modality in bacterial decontamination.

objectiveThis in vitro study was carried out to evaluate the susceptibility of Streptococcus mutans to antibacterial PDT using two different photosensitizers and light sources. MATERIAL AND

methodsStandard suspensions of S. mutans were exposed to laser light at 662 nm and Radachlorin or LED 630 nm in combination with Toluidine blue O (TBO). Radiation-only groups, photosensitizer alone, and groups with no treatment were used as controls. Bacterial suspension from each treatment was subcultured onto the surface of Mueller-Hinton agar plates and bacterial growth was assessed. The results were analyzed by analysis of variance and Tukey test (p<0.05).

resultsPDT with TBO and Radachlorin® significantly reduced S. mutans viability, whereas no difference was observed between two groups of PDT. In the groups treated just with the photosensitizer or irradiated alone, no significant reduction of S. mutans colonies was observed.

conclusionS. mutans colonies were susceptible to either 662 nm laser or LED light in the presence of Radachlorin and TBO respectively with no priority.

Indexed as

LightAnti-Bacterial AgentsCombined Modality TherapyDental CariesLasers, SemiconductorPhotochemotherapyPhotosensitizing AgentsReproducibility of ResultsStreptococcus mutansTime FactorsTolonium ChlorideAnti-Bacterial AgentsPhotosensitizing AgentsTolonium Chloride

Identifiers

PMID24676576
PMCPMC3956397
OpenAlexW1985364144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.