Evidence map›Paper›PMID 24676371›Full record

ArticleArquivos brasileiros de cardiologia2014

Influence of term of exposure to high-fat diet-induced obesity on myocardial collagen type I and III.

Danielle Cristina Tomaz da Silva, Ana Paula Lima-Leopoldo, André Soares Leopoldo, Dijon Henrique Salomé de Campos, André Ferreira do Nascimento, Silvio Assis de Oliveira Junior, Carlos Roberto Padovani, Antonio Carlos Cicogna

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Obesity: A Growing Multifaceted Problem.Arquivos brasileiros de cardiologia · 2015
    Article
  13. Nutrition and cardiology: an interface not to be ignored.Arquivos brasileiros de cardiologia · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Danielle Cristina Tomaz da SilvaDepartamento de Clinica Medica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil.
Ana Paula Lima-LeopoldoDepartamento de Esportes, Centro de Educacao Fisica e Desportos, Universidade Federal do Espirito Santo, Vitoria, ES, Brasil.
André Soares LeopoldoDepartamento de Esportes, Centro de Educacao Fisica e Desportos, Universidade Federal do Espirito Santo, Vitoria, ES, Brasil.
Dijon Henrique Salomé de CamposDepartamento de Clinica Medica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil.
André Ferreira do NascimentoDepartamento de Clinica Medica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil.
Silvio Assis de Oliveira JuniorEscola de Fisioterapia, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil.
Carlos Roberto PadovaniDepartamento de Bioestatistica, Instituto de Ciencias Biologicas, Universidade Estadual Paulista, Botucatu, SP, Brasil.
Antonio Carlos CicognaDepartamento de Clinica Medica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brasil.
Universidade Estadual Paulista (Unesp) · BRUniversidade Federal do Espírito Santo · BRUniversidade Federal de Mato Grosso do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity is a risk factor for many medical complications; medical research has shown that hemodynamic, morphological and functional abnormalities are correlated with the duration and severity of obesity.

objectivePresent study determined the influence of term of exposure to high-fat diet-induced obesity on myocardial collagen type I and III.

methodsThirty-day-old male Wistar rats were randomly distributed into two groups: a control (C) group fed a standard rat chow and an obese (Ob) group alternately fed one of four palatable high-fat diets. Each diet was changed daily, and the rats were maintained on their respective diets for 15 (C15 and Ob15) and 30 (C30 and Ob30) consecutive weeks. Obesity was determined by adiposity index.

resultsThe Ob15 group was similar to the C15 group regarding the expression of myocardial collagen type I; however, expression in the Ob30 group was less than C30 group. The time of exposure to obesity was associated with a reduction in collagen type I in Ob30 when compared with Ob15. Obesity did not affect collagen type III expression.

conclusionThis study showed that the time of exposure to obesity for 30 weeks induced by unsaturated high-fat diet caused a reduction in myocardial collagen type I expression in the obese rats. However, no effect was seen on myocardial collagen type III expression.

Indexed as

Diet, High-FatAdiposityAnimalsBlood PressureBlotting, WesternBody WeightCollagen Type ICollagen Type IIIHeart VentriclesMaleMyocardiumObesityRandom AllocationRats, WistarTime FactorsCollagen Type ICollagen Type III

Identifiers

PMID24676371
PMCPMC3987330
OpenAlexW1895154538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.