ArticleArquivos brasileiros de cardiologia2014
Evaluation of endothelial function on atherosclerosis using perfusion index from pulse oximeter.
Article in Arquivos brasileiros de cardiologia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- From Atheroma to Atherogenic Index, Secular Evidence.Arquivos brasileiros de cardiologia · 2024Article
- Use of Atherogenic Indices as Assessment Methods of Clinical Atherosclerotic Diseases.Arquivos brasileiros de cardiologia · 2023Article
- Do Microvascular Reactivity Studies Contribute to Clinical Practice?Arquivos brasileiros de cardiologia · 2020Article
- Perfusion index for assessing microvascular reactivity in septic shock after fluid resuscitation.Revista Brasileira de terapia intensivaArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndothelial dysfunction is vascular phenomenon that plays an important role in atherosclerosis development. With the purpose of improving the prevention and treatment of atherosclerotic diseases, the searching for accurate, practical and cheaper methods for evaluating endothelial function have become of interest.
objectivesVerify the potential of Peripheral Perfusion Index from pulse oximetry (IPP) as a method of endothelial dysfunction evaluation in patients with atherosclerotic diseases.
methodsThere were recruited 18 control patients and 24 patients with atherosclerotic diseases under optimized treatment, in basic health units. The values of IPP were evaluated before and after an endothelial-dependent stimulus, the reactive hyperemia. The values of IPP were also evaluated in period which the major contribution of Nitric Oxide (NO) for the vasodilation occurs (IPP90-120). The results of IPP were discussed using the literature and estimating their diagnostic and prognostic potential.
resultsThe endothelium-dependent vasodilatory response measured by IPP was significantly lower in patients with atherosclerosis compared to control group, since 45 seconds after reactive hyperemia. Also, the values of IPP90-120 were significantly lower in patients with atherosclerosis [35% (4 - 53%) vs 73% (55 - 169%); p<0,001]. Similarly, the IPP values were lower in atherosclerosis group when it was separated by gender.
conclusionThe results of this study, in association with the low cost of pulse oximeter, suggest a good potential for IPP as an endothelial dysfunction evaluation method. New studies must be done in order to clarify this potential and possibly contribute with the prevention and treatment of atherosclerotic diseases.
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