ArticlePloS one2014
Quantitative stratification of diffuse parenchymal lung diseases.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Use of lung ultrasound surface wave elastography in patients with interstitial lung disease.BMJ open respiratory research · 2026Article
- Long-Term Follow-Up of Interstitial Lung Abnormalities in Low-Dose Chest CT in Health Screening: Exploring the Predictors of Clinically Significant Interstitial Lung Diseases Using Artificial Intelligence-Based Quantitative CT Analysis.Journal of the Korean Society of Radiology · 2024Article
- Interstitial lung abnormalities: new insights between theory and clinical practice.Insights into imaging · 2022Review
- Added benefits of early detection of other diseases on low-dose CT screening.Translational lung cancer research · 2021Review
- Standard spirometry to assess emphysema in patients with chronic obstructive pulmonary disease: the Emphysema Severity Index (ESI).Multidisciplinary respiratory medicine · 2021Article
- Advances in imaging for lung emphysema.Annals of translational medicine · 2020Review
- Prospects and Challenges of Radiomics by Using Nononcologic Routine Chest CT.Radiology. Cardiothoracic imaging · 2020Review
- Assessment of Interstitial Lung Disease Using Lung Ultrasound Surface Wave Elastography: A Novel Technique With Clinicoradiologic Correlates.Journal of thoracic imaging · 2019Article
- Review
- Spirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD.Respiratory research · 2019Article
- Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions.Translational lung cancer research · 2018Review
- Computer-Aided Nodule Assessment and Risk Yield (CANARY) may facilitate non-invasive prediction of EGFR mutation status in lung adenocarcinomas.Scientific reports · 2017Article
- Automated computer-based CT stratification as a predictor of outcome in hypersensitivity pneumonitis.European radiology · 2017Article
- Article
- Appreciating the shades of gray: a case for Computer-Aided Nodule Assessment and Risk Yield (CANARY)-based risk stratification of lung adenocarcinomas.Journal of thoracic disease · 2016Article
- Unsupervised Discovery of Emphysema Subtypes in a Large Clinical Cohort.Machine learning in medical imaging. MLMI (Workshop) · 2016Article
- Multicenter study of quantitative computed tomography analysis using a computer-aided three-dimensional system in patients with idiopathic pulmonary fibrosis.Japanese journal of radiology · 2016Article
- Computer-Aided quantitative analysis in interstitial lung diseases - A pictorial review using CALIPER.Lung India : official organ of Indian Chest SocietyReview
- Outcome Measures for Clinical Trials in Interstitial Lung Diseases.Current respiratory medicine reviewsArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Diffuse parenchymal lung diseases (DPLDs) are characterized by widespread pathological changes within the pulmonary tissue that impair the elasticity and gas exchange properties of the lungs. Clinical-radiological diagnosis of these diseases remains challenging and their clinical course is characterized by variable disease progression. These challenges have hindered the introduction of robust objective biomarkers for patient-specific prediction based on specific phenotypes in clinical practice for patients with DPLD. Therefore, strategies facilitating individualized clinical management, staging and identification of specific phenotypes linked to clinical disease outcomes or therapeutic responses are urgently needed. A classification schema consistently reflecting the radiological, clinical (lung function and clinical outcomes) and pathological features of a disease represents a critical need in modern pulmonary medicine. Herein, we report a quantitative stratification paradigm to identify subsets of DPLD patients with characteristic radiologic patterns in an unsupervised manner and demonstrate significant correlation of these self-organized disease groups with clinically accepted surrogate endpoints. The proposed consistent and reproducible technique could potentially transform diagnostic staging, clinical management and prognostication of DPLD patients as well as facilitate patient selection for clinical trials beyond the ability of current radiological tools. In addition, the sequential quantitative stratification of the type and extent of parenchymal process may allow standardized and objective monitoring of disease, early assessment of treatment response and mortality prediction for DPLD patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.