ArticlePLoS neglected tropical diseases2014
Identification of parasitic communities within European ticks using next-generation sequencing.
Article in PLoS neglected tropical diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Cattle Zoonotic and Non-Zoonotic Tick-Borne Pathogens in Europe-A Retrospective Analysis of the Past 15 Years.Animals : an open access journal from MDPI · 2025Review
- Bacterial blood microbiome ofFrontiers in cellular and infection microbiology · 2025Article
- DNA Barcoding Using 18S rRNA Gene Fragments for Identification of Tick-Borne Protists in Ticks in the Republic of Korea.Pathogens (Basel, Switzerland) · 2024Article
- Coinfection ofPathogens (Basel, Switzerland) · 2024Review
- The specificity of Babesia-tick vector interactions: recent advances and pitfalls in molecular and field studies.Parasites & vectors · 2021Review
- Targeted Next-Generation Sequencing and Informatics as an Effective Tool to Establish the Composition of Bovine Piroplasm Populations in Endemic Regions.Microorganisms · 2020Article
- Article
- Failed Disruption of Tick Feeding, Viability, and Molting after Immunization of Mice and Sheep with RecombinantVaccines · 2020Article
- Combining Citizen Science and Genomics to Investigate Tick, Pathogen, and Commensal Microbiome at Single-Tick Resolution.Frontiers in genetics · 2019Article
- Restriction enzyme digestion of host DNA enhances universal detection of parasitic pathogens in blood via targeted amplicon deep sequencing.Microbiome · 2018Article
- Laboratory colonization stabilizes the naturally dynamic microbiome composition of field collected Dermacentor andersoni ticks.Microbiome · 2017Article
- Ticks and Tick-Borne Pathogens of the Caribbean: Current Understanding and Future Directions for More Comprehensive Surveillance.Frontiers in cellular and infection microbiology · 2017Review
- The bacterial microbiome of Dermacentor andersoni ticks influences pathogen susceptibility.The ISME journal · 2016Article
- Environmental factors influencing tick densities over seven years in a French suburban forest.Parasites & vectors · 2016Article
- Babesia spp. in ticks and wildlife in different habitat types of Slovakia.Parasites & vectors · 2016Article
- Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick-Host Interactions.Trends in parasitology · 2016Review
- Inhibition of the endosymbiont "Candidatus Midichloria mitochondrii" during 16S rRNA gene profiling reveals potential pathogens in Ixodes ticks from Australia.Parasites & vectors · 2015Article
- Babesia spp. and other pathogens in ticks recovered from domestic dogs in Denmark.Parasites & vectors · 2015Article
- Clinical determinants of Lyme borreliosis, babesiosis, bartonellosis, anaplasmosis, and ehrlichiosis in an Australian cohort.International journal of general medicine · 2015Article
- A Comparison between Transcriptome Sequencing and 16S Metagenomics for Detection of Bacterial Pathogens in Wildlife.PLoS neglected tropical diseases · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRisk assessment of tick-borne and zoonotic disease emergence necessitates sound knowledge of the particular microorganisms circulating within the communities of these major vectors. Assessment of pathogens carried by wild ticks must be performed without a priori, to allow for the detection of new or unexpected agents. METHODOLOGY/PRINCIPAL
findingsWe evaluated the potential of Next-Generation Sequencing techniques (NGS) to produce an inventory of parasites carried by questing ticks. Sequences corresponding to parasites from two distinct genera were recovered in Ixodes ricinus ticks collected in Eastern France: Babesia spp. and Theileria spp. Four Babesia species were identified, three of which were zoonotic: B. divergens, Babesia sp. EU1 and B. microti; and one which infects cattle, B. major. This is the first time that these last two species have been identified in France. This approach also identified new sequences corresponding to as-yet unknown organisms similar to tropical Theileria species. CONCLUSIONS/SIGNIFICANCE: Our findings demonstrate the capability of NGS to produce an inventory of live tick-borne parasites, which could potentially be transmitted by the ticks, and uncovers unexpected parasites in Western Europe.
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