Evidence map›Paper›PMID 24675726›Full record

ArticlePloS one2014

The Geogenomic Mutational Atlas of Pathogens (GoMAP) web system.

David P Sargeant, Michael W Hedden, Sandeep Deverasetty, Christy L Strong, Izua J Alaniz, Alexandria N Bartlett, Nicholas R Brandon, Steven B Brooks, Frederick A Brown, Flaviona Bufi and 21 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 1 institution in 1 country.

David P SargeantSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Michael W HeddenSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Sandeep DeverasettySchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Christy L StrongSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Izua J AlanizSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Alexandria N BartlettSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Nicholas R BrandonSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Steven B BrooksSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Frederick A BrownSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Flaviona BufiSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Monika ChakarovaSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Roxanne P DavidSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Karlyn M DobritchSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Horacio P GuerraSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Kelvy S LevitSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Kiran R MathewSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Ray MattiSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Dorothea Q MazaSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Sabyasachy MistrySchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Nemanja NovakovicSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Austin PomerantzSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Timothy F RafalskiSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Viraj RathnayakeSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Noura RezapourSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Christian A RossSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Steve G SchoolerSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Sarah SongaoSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Sean L TuggleSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Helen J WingSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Sandy YousifSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
Martin R SchillerSchool of Life Sciences, University of Nevada Las Vegas, Las Vegas, Nevada, United States of America.
University of Nevada, Las Vegas · US

Funding

Acquisition of computer system for computational biologyS10RR027140 · NCRR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI MORARU, ION I. · 2010 to 2010
$442k
Identification of short functional motifs as potential drug targets for HIVR21AI078708 · NIAID · UNIVERSITY OF NEVADA LAS VEGAS · PI SCHILLER, MARTIN R · 2008 to 2009
$368k
NCRR NIH HHS RR027140NCRR NIH HHS S10 RR027140NIAID NIH HHS AI078708NIAID NIH HHS R21 AI078708NIDDK NIH HHS DK078735NIGMS NIH HHS GM07689
6 · The paper itself

Abstract

We present a new approach for pathogen surveillance we call Geogenomics. Geogenomics examines the geographic distribution of the genomes of pathogens, with a particular emphasis on those mutations that give rise to drug resistance. We engineered a new web system called Geogenomic Mutational Atlas of Pathogens (GoMAP) that enables investigation of the global distribution of individual drug resistance mutations. As a test case we examined mutations associated with HIV resistance to FDA-approved antiretroviral drugs. GoMAP-HIV makes use of existing public drug resistance and HIV protein sequence data to examine the distribution of 872 drug resistance mutations in ∼ 502,000 sequences for many countries in the world. We also implemented a broadened classification scheme for HIV drug resistance mutations. Several patterns for geographic distributions of resistance mutations were identified by visual mining using this web tool. GoMAP-HIV is an open access web application available at http://www.bio-toolkit.com/GoMap/project/

Indexed as

Databases, GeneticGenome, MicrobialMutationWeb BrowserCommunicable DiseasesGenomicsGeographyGlobal HealthHIV InfectionsHumansPopulation Surveillance

Identifiers

PMID24675726
PMCPMC3968042
OpenAlexW2319584291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.