ArticleNature genetics2014
Ancient human oral plaque preserves a wealth of biological data.
Article in Nature genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- The genomic history of Streptococcus mutans from the Mesolithic until modern times.Genome biology · 2026Article
- An extensive archaeological dental calculus dataset spanning 5000 years for ancient human oral microbiome research.Data in brief · 2025Article
- Reconstructing medieval diets through the integration of stable isotope and proteomic analyses from two European burial sites.Scientific reports · 2025Article
- Oral microbiome in human health and diseases.mLife · 2024Review
- Dental calculus in the industrial age: Human dental calculus in the Post-Medieval period, a case study from industrial Manchester.Quaternary international : the journal of the International Union for Quaternary Research · 2023Article
- Paleoproteomic evidence reveals dairying supported prehistoric occupation of the highland Tibetan Plateau.Science advances · 2023Article
- Exploring late Paleolithic and Mesolithic diet in the Eastern Alpine region of Italy through multiple proxies.American journal of physical anthropology · 2021Article
- Dental Calculus as a Potential Biosource for Human Papillomavirus Detection in Oral Squamous Cell Carcinoma.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Metagenomic analysis of dental calculus in ancient Egyptian baboons.Scientific reports · 2019Article
- Oral microbiomes: more and more importance in oral cavity and whole body.Protein & cell · 2018Review
- Article
- What could you do with 400 years of biological history on african americans? Evaluating the potential scientific benefit of systematic studies of dental and skeletal materials on African Americans from the 17th through 20th centuries.American journal of human biology : the official journal of the Human Biology Council · 2016Article
- Exploring Relationships between Host Genome and Microbiome: New Insights from Genome-Wide Association Studies.Frontiers in microbiology · 2016Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new study explores the ancient oral microbiome from the well-preserved dental calculus samples of four human individuals who lived during medieval times, using a suite of genomic, proteomic and microscopic approaches. The authors investigate the evolution of dental pathogens by reconstructing the genome of the periodontal pathogen Tannerella forsythia and also identify antibiotic resistance genes, bacterial virulence factors and host immune defense proteins.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.