ArticleDiagnostic and interventional radiology (Ankara, Turkey)
Angioplasty for pediatric renovascular hypertension: a 13-year experience.
Article in Diagnostic and interventional radiology (Ankara, Turkey). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04137614 (The Effects and Safety of Drug-coated Balloon in the Treatment of Hypertension Caused by Takayasu Arteritis Associated Renal Artery Stenosis), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects and Safety of Drug-coated Balloon in the Treatment of Hypertension Caused by Takayasu Arteritis Associated Renal Artery Stenosis: a Single Centre, Random, Double Blind Trial
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- The clinical and radiological cerebrovascular abnormalities associated with renovascular hypertension in children: a systematic review.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Aorto-Renal Dysplasia in Childhood: The Overlap of Neurofibromatosis Type 1 and Pediatric Renovascular Hypertension.Current hypertension reports · 2026Review
- Mid-to-long term outcomes following renal artery angioplasty in children and young adults with renal artery stenosis: a retrospective review.Pediatric nephrology (Berlin, Germany) · 2025Article
- Endovascular salvage of renal artery bypass in pediatric a patient with neurofibromatosis type 1.Journal of vascular surgery cases and innovative techniques · 2025Article
- A Case of Hyponatremic Hypertensive Syndrome With Neurologic Sequelae Secondary to Unilateral Renal Artery Stenosis.Cureus · 2024Article
- Cardiovascular outcomes improve in children with renovascular hypertension following endovascular and surgical interventions.Pediatric nephrology (Berlin, Germany) · 2024Observational
- Drug-coated balloon for treatment of non-atherosclerotic renal artery stenosis-a multi-center study.BMC cardiovascular disorders · 2023Article
- Outcomes of percutaneous transluminal renal angioplasty for pediatric renovascular hypertension: a 12-year retrospective single-center experience.Translational pediatrics · 2023Article
- Hypertension crisis as the first symptom of renovascular hypertension in children.Italian journal of pediatrics · 2022Article
- Presentation, treatment, and outcome of renovascular hypertension below 2 years of age.European journal of pediatrics · 2022Article
- An Update on Childhood-Onset Takayasu Arteritis.Frontiers in pediatrics · 2022Review
- Renovascular hypertension in pediatric patients: update on diagnosis and management.Pediatric nephrology (Berlin, Germany) · 2021Review
- Timing of procedural interventions in childhood renovascular hypertension.Pediatric nephrology (Berlin, Germany) · 2021Article
- Renovascular hypertension in children.CVIR endovascular · 2021Review
- Surgical management of pediatric renin-mediated hypertension secondary to renal artery occlusive disease and abdominal aortic coarctation.Journal of vascular surgery · 2020Article
- Efficacy of Antihypertensive Therapy in a Child with Unilateral Focal Fibromuscular Dysplasia of the Renal Artery: A Case Study and Review of Literature.Medicines (Basel, Switzerland) · 2020Article
- Childhood-onset Takayasu Arteritis.European journal of rheumatology · 2020Article
- Unilateral renal artery stenosis presented with hyponatremic-hypertensive syndrome - case report and literature review.BMC nephrology · 2019Article
- Renal autotransplantation for the management of renal artery in-stent restenosis in an adult patient with Takayasu arteritis.BMJ case reports · 2018Article
- Imaging studies in pediatric fibromuscular dysplasia (FMD): a single-center experience.Pediatric nephrology (Berlin, Germany) · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to evaluate the long-term outcome and efficacy of percutaneous transluminal renal angioplasty (PTRA) for pediatric renal artery stenosis (RAS), which is an important cause of medication-refractory pediatric hypertension. MATERIALS AND
methodsWe retrospectively evaluated 22 hypertensive children (age range, 3-17 years) who underwent PTRA from February 2000 to July 2012. Sixteen patients had Takayasu arteritis and six fibromuscular dysplasia. Five were not included in the statistical analysis due to loss to follow-up.
resultsTechnical success was achieved in 32 of 34 procedures (94.1%). The stenosis rate decreased from 84.5% before PTRA to 20.1% after PTRA. Treatment was effective in 72.7% (16/22) of patients, including complete cure in 27.3% (6/22) and improvement in 45.5% (10/22). Systolic and diastolic blood pressures decreased from 153 ± 19.1 to 131.7 ± 21.4 mmHg and from 97.9 ± 14.2 to 83.6 ± 19.3 mmHg, respectively (P <0.01). Number of antihypertensive agents decreased from 2.7 to 0.5 per patient. Restenosis was detected in 40.9% (9/22) of patients, with a restenotic interval of 11.8 months (range, 3-47 months). Lesion length was strongly correlated with clinical success (cure and improvement) (independent-sample t test, P <0.001; binary logistic regression, P = 0.040).
conclusionLesion length is an important determination of clinical success with PTRA for pediatric RAS. PTRA is an appropriate treatment option for pediatric renovascular hypertension due to Takayasu arteritis and fibromuscular dysplasia.
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