Evidence map›Paper›PMID 24674812›Full record

ReviewSchizophrenia bulletin2014

Unlocking the treasure trove: from genes to schizophrenia biology.

Shane E McCarthy, W Richard McCombie, Aiden Corvin

Abstract readReview
In one paragraph

Review in Schizophrenia bulletin, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Marital Satisfaction as a Moderator of Molecular Genetic Influences on Mental Health.Clinical psychological science : a journal of the Association for Psychological Science · 2021
    Article
  4. Review
  5. Review
  6. Review
  7. Recent genetic findings in schizophrenia and their therapeutic relevance.Journal of psychopharmacology (Oxford, England) · 2015
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shane E McCarthy*To whom correspondence should be addressed; Department of Psychiatry & Neuropsychiatric Genetics Research Group, Institute of Molecular Medicine, Trinity College Dublin, Dublin 2, Ireland; tel: +353-1-8962467, fax: +353-1-8963405, e-mail: acorvin@tcd.ie.
W Richard McCombie
Aiden Corvin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant progress is being made in defining the genetic etiology of schizophrenia. As the list of implicated genes grows, parallel developments in gene editing technology provide new methods to investigate gene function in model systems. The confluence of these two research fields--gene discovery and functional biology--may offer novel insights into schizophrenia etiology. We review recent advances in these fields, consider the likely obstacles to progress, and consider strategies as to how these can be overcome.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsGenetic Predisposition to DiseaseGenotypeHumansPhenotypeSchizophreniaSequence Analysis, DNACRISPRgenomicsmodelschizophreniasequencingsystems

Identifiers

PMID24674812
PMCPMC3984532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.