ReviewExperimental hematology2014
Snail transcription factors in hematopoietic cell development: a model of functional redundancy.
Review in Experimental hematology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
- Role of epithelial-mesenchymal transition (EMT) in malignancies: current status and future prospects.Signal transduction and targeted therapy · 2026Review
- Transcriptome remodeling of mouse hearts during postnatal cardiac maturation and under proteotoxic stress.Molecular biology reports · 2026Article
- EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation.Nucleic acids research · 2025Article
- The Role of Epithelial-to-Mesenchymal Transition Transcription Factors (EMT-TFs) in Acute Myeloid Leukemia Progression.Biomedicines · 2024Review
- Epithelial-to-mesenchymal plasticity from development to disease: An introduction to the special issue.Genesis (New York, N.Y. : 2000) · 2024Article
- Heterogeneity and plasticity of epithelial-mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms.Cell proliferation · 2023Review
- Regulatory Programs of B-cell Activation and Germinal Center Reaction Allow B-ALL Escape from CD19 CAR T-cell Therapy.Cancer immunology research · 2022Article
- Prognostic values of SNAI family members in breast cancer patients.Annals of translational medicine · 2020Article
- Twist1 mediated regulation of glioma tumorigenicity is dependent on mode of mouse neural progenitor transformation.Oncotarget · 2017Article
- What's Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism.Molecular cell · 2016Review
- Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs.Immunobiology · 2016Article
- Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3.Cellular immunology · 2015Article
- Epidermal growth factor signaling in transformed cells.International review of cell and molecular biology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Coordinated gene expression is crucial in facilitating proper lymphoid cell development and function. The precise patterns of gene expression during B- and T-cell development are regulated through a complex interplay between a multitude of transcriptional regulators, both activators and repressors. We have recently identified the Snail family of transcription factors as playing significant and overlapping roles in lymphoid cell development, in that deletion of both SNAI2 and SNAI3 was required to fully impact the generation of mature T and B cells. Analyses using compound heterozygote animals further demonstrated that SNAI2 and SNAI3 were partially haplosufficient and relatively equivalent in their ability to preserve B-cell generation in the bone marrow. In this review, we summarize studies elucidating the role of the Snail family in hematopoiesis, with a focus on lymphoid cell development. Using the Snail family as an example, we discuss the concepts of functional redundancy and strategies employed to assay transcription factor families for intramember compensation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.