Evidence map›Paper›PMID 24674455›Full record

Trial reportBasic & clinical pharmacology & toxicology2014

Can physical exercise or food deprivation cause release of fat-stored cannabinoids?

Andreas Austgulen Westin, George Mjønes, Ola Burchardt, Ole Martin Fuskevåg, Lars Slørdal

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Basic & clinical pharmacology & toxicology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Andreas Austgulen WestinDepartment of Clinical Pharmacology, St. Olav University Hospital, Trondheim, Norway.
George Mjønes
Ola Burchardt
Ole Martin Fuskevåg
Lars Slørdal
Norges Røde Kors · NONorwegian University of Science and Technology · NOSt Olav's University Hospital · NOUniversity Hospital of North Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate whether physical exercise or food deprivation may increase cannabinoid levels in serum or urine in abstinent chronic cannabis users. The study took place in a drug detoxification ward parallel to study participants receiving treatment. Six chronic, daily cannabis users (one female, five males, average age 30.0 years; BMI 20.8) were exposed to a 45-min. moderate-intensity workout and a 24-hr period of food deprivation. Serum samples were drawn prior to and after interventions and analysed for ∆9-tetrahydrocannabinol (THC) and 11-nor-9-carboxy-∆9-tetrahydrocannabinol (THCCOOH) by liquid chromatography-tandem mass spectrometry (LCMSMS), and all voided urine was tested for THCCOOH by LCMSMS and normalized to the creatinine levels, yielding ng/mg ratios. There were no major differences in the measured cannabinoid levels in serum or urine before and after physical exercise or food deprivation. We conclude that exercise and/or food deprivation are unlikely to cause sufficient cannabinoid concentration changes to hamper correct interpretations in drug testing programmes.

Indexed as

AdultCannabinoidsChromatography, LiquidDronabinolExerciseFemaleFood DeprivationHumansMaleMarijuana SmokingSubstance Abuse DetectionTandem Mass Spectrometry11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acidCannabinoidsDronabinol

Identifiers

PMID24674455
PMCPMC4270258
OpenAlexW1979778439

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.