Evidence map›Paper›PMID 24672797›Full record

ArticleBioMed research international2014

Effects of Momordica charantia L. on the blood rheological properties in diabetic patients.

Eduardo Luzía França, Elton Brito Ribeiro, Edson Fredulin Scherer, Déborah Giovanna Cantarini, Rafael Souza Pessôa, Fernando Luzía França, Adenilda Cristina Honorio-França

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Hematological and biochemical parameters correlated to hemorheology in Canine Monocytic Ehrlichiosis.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The Effect ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Eduardo Luzía FrançaInstitute of Biological and Health Science, Federal University of Mato Grosso (UFMT), Rodovia BR070, Km 5 s/n º , 78600-000 Barra do Garças-MT, Brazil.
Elton Brito RibeiroInstitute of Biological and Health Science, Federal University of Mato Grosso (UFMT), Rodovia BR070, Km 5 s/n º , 78600-000 Barra do Garças-MT, Brazil.
Edson Fredulin SchererInstitute of Biological and Health Science, Federal University of Mato Grosso (UFMT), Rodovia BR070, Km 5 s/n º , 78600-000 Barra do Garças-MT, Brazil.
Déborah Giovanna CantariniInstitute of Biological and Health Science, Federal University of Mato Grosso (UFMT), Rodovia BR070, Km 5 s/n º , 78600-000 Barra do Garças-MT, Brazil.
Rafael Souza PessôaInstitute of Biological and Health Science, Federal University of Mato Grosso (UFMT), Rodovia BR070, Km 5 s/n º , 78600-000 Barra do Garças-MT, Brazil.
Fernando Luzía FrançaFederal University of Ouro Preto, Ouro Preto, MG, Brazil.
Adenilda Cristina Honorio-FrançaInstitute of Biological and Health Science, Federal University of Mato Grosso (UFMT), Rodovia BR070, Km 5 s/n º , 78600-000 Barra do Garças-MT, Brazil.
Universidade Federal de Mato Grosso · BRUniversidade Federal de Ouro Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An evaluation of the rheological properties and the effects of Momordica. charantia L. (M. charantia) nanoparticles and polyethylene glycol (PEG) microspheres adsorbed with M. charantia nanoparticles on the blood of hyperglycemic patients is presented. Blood samples were collected according to glycemic status: normoglycemic (N = 56) and hyperglycemic (N = 26). General and hematological characteristics were determined. Blood rheological parameters were determined at room temperature and under a temperature scan. We determined the effects on whole blood viscosity of treatment with an extract of M. charantia, PEG, or PEG microspheres adsorbed with plant extract. The viscosity of the blood of hyperglycemic patients is greater than that of normoglycemic patients. Nanoparticles of M. charantia extracts lowered blood viscosity at equivalent rates in normo- and hyperglycemic individuals. PEG microspheres did not reduce blood viscosity in hyperglycemic individuals. However, PEG microspheres adsorbed with nanofraction extracts of M. charantia reduced blood viscosity. These data suggest that the effects of diabetes on the viscosity of the blood should be considered. The use of a nanoparticles extract of M. charantia and its adsorption on PEG microspheres may represent an alternative for the control and treatment of blood disorders in diabetic patients.

Indexed as

AdultBlood ViscosityDiabetes Mellitus, Type 2HemorheologyHumansHyperglycemiaMiddle AgedMomordica charantiaPlant ExtractsTemperaturePlant Extracts

Identifiers

PMID24672797
PMCPMC3930187
OpenAlexW2085540647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.