Evidence map›Paper›PMID 24672787›Full record

ArticleBioMed research international2014

Automated identification of dementia using FDG-PET imaging.

Yong Xia, Shen Lu, Lingfeng Wen, Stefan Eberl, Michael Fulham, David Dagan Feng

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Yong XiaShaanxi Provincial Key Lab of Speech & Image Information Processing (SAIIP), School of Computer Science, Northwestern Polytechnical University, Xi'an 710072, China ; Biomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, The University of Sydney, Sydney, NSW 2006, Australia ; Department of Molecular Imaging, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia.ORCID 0000-0002-8427-4935
Shen LuBiomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0001-9375-380X
Lingfeng WenBiomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, The University of Sydney, Sydney, NSW 2006, Australia ; Department of Molecular Imaging, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia.
Stefan EberlBiomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, The University of Sydney, Sydney, NSW 2006, Australia ; Department of Molecular Imaging, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia.ORCID 0000-0001-6069-7530
Michael FulhamBiomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, The University of Sydney, Sydney, NSW 2006, Australia ; Department of Molecular Imaging, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia ; Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia.
David Dagan FengBiomedical and Multimedia Information Technology (BMIT) Research Group, School of Information Technologies, The University of Sydney, Sydney, NSW 2006, Australia ; Med-X Research Institute, Shanghai Jiao Tong University, Shanghai 200030, China.
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parametric FDG-PET images offer the potential for automated identification of the different dementia syndromes. However, various existing image features and classifiers have their limitations in characterizing and differentiating the patterns of this disease. We reported a hybrid feature extraction, selection, and classification approach, namely, the GA-MKL algorithm, for separating patients with suspected Alzheimer's disease and frontotemporal dementia from normal controls. In this approach, we extracted three groups of features to describe the average level, spatial variation, and asymmetry of glucose metabolic rates in 116 cortical volumes. An optimal combination of features, that is, capable of classifying dementia cases was identified by a genetic algorithm- (GA-) based method. The condition of each FDG-PET study was predicted by applying the selected features to a multikernel learning (MKL) machine, in which the weighting parameter of each kernel function can be automatically estimated. We compared our approach to two state-of-the-art dementia identification algorithms on a set of 129 clinical cases and improved the performance in separating the dementia types, achieving accuracy of 94.62%. There is a very good agreement between the proposed automated technique and the diagnosis made by clinicians.

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyAlgorithmsArtificial IntelligenceAutomationDatabases as TopicDementiaHumansFluorodeoxyglucose F18

Identifiers

PMID24672787
PMCPMC3929290
OpenAlexW2081347040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.