Evidence map›Paper›PMID 24672652›Full record

ReviewGut and liver2014

Population screening for colorectal cancer means getting FIT: the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT).

James E Allison, Callum G Fraser, Stephen P Halloran, Graeme P Young

2 registry-linked trialsOpen access · diamondAbstract readReview
In one paragraph

Review in Gut and liver, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 87 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 4 pooled it
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05609396 nacompletednot on this mapstarted 2022, after this paper: background citation

Interventions to Improve Bowel Cancer Screening Uptake in Ireland: a 2x2 Factorial Trial

TypeinterventionalSponsorDublin City UniversityRan2022 to 2022Enrolled8,734ConditionsColorectal CancerArmsBehaviorally enhanced reminder letter
NCT05661292 unknown statusnot on this mapstarted 2019, after this paper: background citation

Validation of Advanced Colorectal Neoplasm Risk Categories in Screening Colonoscopy and Identification of Biomarkers in a Prospective Cohort in Mexico.

TypeobservationalSponsorInstituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranRan2019 to 2025Enrolled2,000ConditionsColorectal Cancer ScreeningArmsFecal inmunochemical test, Colonoscopy, Optional collection of tissue, blood and urine for future biomedical research
3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 4 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Pooled it
  2. A Systematic Review of Repeat Fecal Occult Blood Tests for Colorectal Cancer Screening.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Improving Fecal Immunochemical Test Collection for Colorectal Cancer Screening During the COVID-19 Pandemic.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James E AllisonDivision of Gastroenterology, University of California San Francisco School of Medicine, San Francisco, CA, USA. ; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.
Callum G FraserCentre for Research into Cancer Prevention and Screening, University of Dundee School of Medicine, Dundee, Scotland.
Stephen P HalloranNHS Bowel Cancer Screening Southern Programme Hub, Royal Surrey County Hospital and University of Surrey, Guildford, UK.
Graeme P YoungFlinders Centre for Innovation in Cancer, Flinders University, Bedford Park SA, Australia.
Flinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors? What evidence supports its adoption? How can this evidence best be used? This review addresses these questions and provides an understanding of FIT theory and practices to expedite international efforts to implement the use of FIT in CRC screening.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerFecesForecastingGlobal HealthHemoglobinsHumansImmunochemistryMass ScreeningOccult BloodSensitivity and SpecificityHemoglobinsColorectal cancerColorectal cancer screeningFecal immunochemical test for hemoglobinPopulation screening

Identifiers

PMID24672652
PMCPMC3964261
OpenAlexW2112049479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.