ReviewFrontiers in synaptic neuroscience2014
The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease.
Review in Frontiers in synaptic neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Review
- Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Untangling the Conformational Plasticity of V66M Human proBDNF Polymorphism as a Modifier of Psychiatric Disorder Susceptibility.International journal of molecular sciences · 2022Article
- Duration of Social Isolation Affects Production of Nitric Oxide in the Rat Brain.International journal of molecular sciences · 2021Article
- A Non-Invasive Determination of Ketosis-Induced Elimination of Chronic Daytime Somnolence in a Patient with Late-Stage Dementia (Assessed with Type 3 Diabetes): A Potential Role of Neurogenesis.Journal of Alzheimer's disease reports · 2021Article
- Flavonoids as a Natural Enhancer of Neuroplasticity-An Overview of the Mechanism of Neurorestorative Action.Antioxidants (Basel, Switzerland) · 2020Review
- Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia.Neuroreport · 2020Article
- NGL-1/LRRC4C-Mutant Mice Display Hyperactivity and Anxiolytic-Like Behavior Associated With Widespread Suppression of Neuronal Activity.Frontiers in molecular neuroscience · 2019Article
- In silico analysis of the V66M variant of human BDNF in psychiatric disorders: An approach to precision medicine.PloS one · 2019Article
- The tetrapartite synapse: a key concept in the pathophysiology of schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2018Review
- Mechanism involved in insulin resistance via accumulation of β-amyloid and neurofibrillary tangles: link between type 2 diabetes and Alzheimer's disease.Drug design, development and therapy · 2018Review
- FGF-FGFR Mediates the Activity-Dependent Dendritogenesis of Layer IV Neurons during Barrel Formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- The Wnt receptor Ryk is a negative regulator of mammalian dendrite morphogenesis.Scientific reports · 2017Article
- Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis.Frontiers in synaptic neuroscience · 2017Article
- Maternal Diabetes Alters Expression of MicroRNAs that Regulate Genes Critical for Neural Tube Development.Frontiers in molecular neuroscience · 2017Article
- The Evidence for Altered BDNF Expression in the Brain of Rats Reared or Housed in Social Isolation: A Systematic Review.Frontiers in behavioral neuroscience · 2017Review
- The Planar Cell Polarity Transmembrane Protein Vangl2 Promotes Dendrite, Spine and Glutamatergic Synapse Formation in the Mammalian Forebrain.Molecular neuropsychiatry · 2016Article
- Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice.Behavioural brain research · 2016Article
- In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders.Neural plasticity · 2016Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Growth factors play important roles in synapse formation. Mouse models of neuropsychiatric diseases suggest that defects in synaptogenic growth factors, their receptors, and signaling pathways can lead to disordered neural development and various behavioral phenotypes, including anxiety, memory problems, and social deficits. Genetic association studies in humans have found evidence for similar relationships between growth factor signaling pathways and neuropsychiatric phenotypes. Accumulating data suggest that dysfunction in neuronal circuitry, caused by defects in growth factor-mediated synapse formation, contributes to the susceptibility to multiple neuropsychiatric diseases, including epilepsy, autism, and disorders of thought and mood (e.g., schizophrenia and bipolar disorder, respectively). In this review, we will focus on how specific synaptogenic growth factors and their downstream signaling pathways might be involved in the development of neuropsychiatric diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.