ArticleVascular health and risk management2014
Association of hypertension and obesity with HIV and antiretroviral therapy in a rural tertiary health center in Nigeria: a cross-sectional cohort study.
Article in Vascular health and risk management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 6 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 6 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta-analysis.HIV medicine · 2026Pooled it
- Hypertension among people living with human immunodeficiency virus in sub-Saharan Africa: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Does Engagement in HIV Care Affect Screening, Diagnosis, and Control of Noncommunicable Diseases in Sub-Saharan Africa? A Systematic Review and Meta-analysis.AIDS and behavior · 2024Pooled it
- Patho-immune Mechanisms of Hypertension in HIV: a Systematic and Thematic Review.Current hypertension reports · 2019Pooled it
- Pooled it
- Prevention of cardiovascular disease among people living with HIV in sub-Saharan Africa.Progress in cardiovascular diseasesPooled it
- Prevalence and associated factors of overweight and obesity among people living with HIV on antiretroviral therapy in a national hospital in Benin.Scientific reports · 2025Article
- Prevalence and associated factors of hypertension among people living with HIV/AIDS on antiretroviral therapy in Benin's National Teaching Hospital.Scientific reports · 2024Article
- The burden of non-communicable diseases among people living with HIV in Sub-Saharan Africa: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: a protocol for a systematic review.Systematic reviews · 2023Article
- Hypertension and associated factors among patients attending HIV clinic at Korle-Bu Teaching Hospital.Ghana medical journal · 2023Article
- Potential risk factors for cardiovascular diseases and associated sociodemographic characteristics: A cross-sectional evaluation of a large cohort of women living with HIV in north-central Nigeria.PLOS global public health · 2023Article
- Prevalence and control of hypertension among people living with HIV receiving care at a Nigerian hospital.The Pan African medical journal · 2022Article
- Prevalence of diabetes mellitus and hypertension amongst the HIV-positive population at a district hospital in eThekwini, South Africa.African journal of primary health care & family medicine · 2021Article
- HIV and cardiovascular disease in sub-Saharan Africa: Demographic and Health Survey data for 4 countries.BMC public health · 2021Article
- Association between Blood Pressure and HIV Status in Rural Uganda: Results of Cross-Sectional Analysis.Global heart · 2021Article
- A comparative analysis of blood pressure in HIV-infected patients versus uninfected controls residing in Sub-Saharan Africa: a narrative review.Journal of human hypertension · 2020Review
- The interaction between detectable plasma viral load and increased body mass index on hypertension among persons living with HIV.AIDS care · 2020Article
- Behavioral risk factors for hypertension among adults living with HIV accessing care in secondary health facilities in Lagos State, Nigeria.Journal of family medicine and primary care · 2020Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are few studies from Nigeria and Africa regarding the contribution of obesity and hypertension to cardiovascular risk in HIV-infected patients. This study investigates the prevalence of hypertension and obesity and their association with HIV infection and antiretroviral treatment (ART).
methodsWe conducted a cross-sectional cohort study in a rural tertiary health center in Nigeria. The data collected included demographic variables, blood pressure, body mass index (BMI), monthly income, educational attainment, HIV status and ART treatment, duration of treatment, and CD4 T-lymphocyte count.
resultsA total of 403 participants met the inclusion criteria. There were 153 (38.0%) HIV-negative subjects (42.5% male, 57.5% female; mean age: 35.5 ± 7.6 years), 120 (29.8%) HIV-positive drug-naïve subjects (42.5% male, 57.5% female; mean age: 36.5 ± 9.1 years), and 130 (32.2%) HIV-positive subjects taking antiretroviral drugs (33.1% male, 66.9% female; mean age: 38.6 ± 8.0 years). The prevalence of hypertension was 13.7% in HIV-negative subjects, 19.0% in HIV-positive drug-naïve subjects, and 12.3% in HIV-positive ART subjects. The prevalence of obesity was 15.9% in the HIV-negative group, 3% in the HIV-positive drug-naïve group, and 8% in the HIV-positive ART group. Multivariate regression analysis showed no relationship between hypertension and HIV status (P=0.293) or ART status (P=0.587). In contrast, BMI showed a strong relationship with HIV status (odds ratio: 0.281; 95% confidence interval: 0.089-0.884; P=0.030) but not with ART status (P=0.593). BMI was a significant predictor of hypertension.
conclusionHIV or ART status was not associated with hypertension. HIV infection was associated with a lower BMI, and a lower prevalence of obesity compared with HIV-negative subjects.
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