ArticleOpen biology2014
Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni.
Article in Open biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed.
- Research progress on nanomaterials in promoting phage function and application.Applied and environmental microbiology · 2026Review
- Prophages and their interactions with lytic phages in the human gut microbiota and their impact on microbial diversity, gut health, and disease.Applied and environmental microbiology · 2025Review
- Effects of bacteriophages on gut microbiome functionality.Gut microbes · 2025Review
- Article
- Aerotolerancy ofPathogens (Basel, Switzerland) · 2024Review
- Symbiosis of a lytic bacteriophage andApplied and environmental microbiology · 2024Article
- Host and nonhost bacteria support bacteriophage dissemination along mycelia and abiotic dispersal networks.microLife · 2024Article
- Phage-Based Biosanitation Strategies for Minimizing PersistentAnimals : an open access journal from MDPI · 2023Review
- Article
- Bacteriophages of Mycobacterium tuberculosis, their diversity, and potential therapeutic uses: a review.BMC infectious diseases · 2022Review
- Mutualistic interplay between bacteriophages and bacteria in the human gut.Nature reviews. Microbiology · 2022Review
- The coordination of anti-phage immunity mechanisms in bacterial cells.Nature communications · 2022Article
- Bacteriophages and their potential for treatment of gastrointestinal diseases.Nature reviews. Gastroenterology & hepatology · 2022Review
- Village-Indigenous Chicken Bacterial Carriage after the Heavy Rains of 2018, Kenya: Indicator on Environmental Contamination with Pathogenic/Zoonotic Bacteria.Veterinary medicine international · 2022Article
- Article
- Black box of phage-bacterium interactions: exploring alternative phage infection strategies.Open biology · 2021Review
- Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis.BMC biology · 2021Article
- Isolation and characterisation of ΦcrAss002, a crAss-like phage from the human gut that infects Bacteroides xylanisolvens.Microbiome · 2021Article
- Phage Biocontrol of Campylobacter: A One Health Approach.Current topics in microbiology and immunology · 2021Review
- Application of Bacteriophages to LimitFrontiers in microbiology · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Members of the genus Campylobacter are frequently responsible for human enteric disease, often through consumption of contaminated poultry products. Bacteriophages are viruses that have the potential to control pathogenic bacteria, but understanding their complex life cycles is key to their successful exploitation. Treatment of Campylobacter jejuni biofilms with bacteriophages led to the discovery that phages had established a relationship with their hosts typical of the carrier state life cycle (CSLC), where bacteria and bacteriophages remain associated in equilibrium. Significant phenotypic changes include improved aerotolerance under nutrient-limited conditions that would confer an advantage to survive in extra-intestinal environments, but a lack in motility eliminated their ability to colonize chickens. Under these circumstances, phages can remain associated with a compatible host and continue to produce free virions to prospect for new hosts. Moreover, we demonstrate that CSLC host bacteria can act as expendable vehicles for the delivery of bacteriophages to new host bacteria within pre-colonized chickens. The CSLC represents an important phase in the ecology of Campylobacter bacteriophage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.