Evidence map›Paper›PMID 24671924›Full record

ArticlePharmacoEconomics2014

Using the EuroQol EQ-5D in Swiss cancer patients, which value set should be applied?

Klazien Matter-Walstra, Dirk Klingbiel, Thomas Szucs, Bernhard C Pestalozzi, Matthias Schwenkglenks

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in PharmacoEconomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Developing a patient-based utility value set for the EORTC QLU-C10D using the OPUF method in Chinese cancer patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  4. Article
  5. Article
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  7. COVID-19-related health utility values and changes in COVID-19 patients and the general population: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
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  9. Article
  10. Observational
  11. Article
  12. Article
  13. A Meta-Regression Analysis of Utility Weights for Breast Cancer: The Power of Patients' Experience.International journal of environmental research and public health · 2020
    Article
  14. Article
  15. Two-year outcome comparison of decompression in 14 lipomatosis cases with 169 degenerative lumbar spinal stenosis cases: a Swiss prospective multicenter cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020
    Article
  16. Symptoms and quality of life in patients with coexistent atrial fibrillation and atrial flutter.International journal of cardiology. Heart & vasculature · 2020
    Article
  17. Article
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  19. Observational
  20. The impact of low back pain on health-related quality of life in old age: results from a survey of a large sample of Swiss elders living in the community.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Klazien Matter-WalstraInstitute of Pharmaceutical Medicine/ECPM, University of Basel, Klingelbergstrasse 61, 4056, Basel, Switzerland, klazien.matter@unibas.ch.
Dirk Klingbiel
Thomas Szucs
Bernhard C Pestalozzi
Matthias Schwenkglenks
University of Basel · CHSwiss Group For Clinical Cancer Research · CHUniversity Hospital of Zurich · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe European Quality of Life-5 Dimensions (EQ-5D) instrument combines questionnaire responses into a single utility estimate using country-specific value sets. Countries without a national value set are advised to select one based on geographic proximity. In the absence of a Swiss value set, we used foreign value sets to gain insights into their appropriateness for use with Swiss cancer patients.

methodsEQ-5D health states and visual analogue scale (VAS) ratings were collected in one German and three Swiss oncology trials. Utilities were calculated based on the United Kingdom (UK), German (GE), French (FR) and European Union (EU) value sets. Resulting differences and Pearson partial correlation coefficients with corresponding VAS ratings were assessed.

resultsIn total, 202 Swiss and 154 German patients undergoing cancer treatment completed at least two EQ-5D forms. The mean difference between GE-based and FR-, UK- or EU-based utilities was significantly larger than the differences between the latter. The absolute mean difference between utilities and VAS ratings was highest for GE-based utilities, for Swiss (0.170, 95 % confidence interval [CI] 0.146-0.194) and German patients (0.174, 95 % CI 0.145-0.202). The correlation between GE-based utilities and VAS ratings was the lowest (r = 0.36, 95 % CI 0.33-0.40); the highest was between FR-based utilities and VAS ratings (r = 0.43, 95 % CI 0.39-0.46).

conclusionFor Switzerland, utility calculations based on the German or French value set would be an obvious choice. Our results suggest that the German value set may not be the most appropriate for use with Swiss cancer patients. The French and EU value sets may be relevant alternatives and improve international comparability.

Indexed as

Quality of LifeAdultAgedAged, 80 and overCost-Benefit AnalysisEuropeFemaleGermanyHealth StatusHumansMaleMiddle AgedNeoplasmsQuality-Adjusted Life YearsSurveys and QuestionnairesSwitzerland

Identifiers

PMID24671924
OpenAlexW1994295098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.