Evidence map›Paper›PMID 24670478›Full record

ArticleInternational journal of molecular sciences2014

Endothelialization of novel magnesium-rare earth alloys with fluoride and collagen coating.

Nan Zhao, Benjamin Workman, Donghui Zhu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Magnesium Regulates Endothelial Barrier Functions through TRPM7, MagT1, and S1P1.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Article
  8. Article
  9. Article
  10. A preliminary study for novel use of two Mg alloys (WE43 and Mg3Gd).Journal of materials science. Materials in medicine · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nan ZhaoDepartment of Chemical, Biological and Bio-Engineering, NSF Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA. nzhao@aggies.ncat.edu.
Benjamin WorkmanDepartment of Chemical, Biological and Bio-Engineering, NSF Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA. bdworkma@live.unc.edu.
Donghui ZhuDepartment of Chemical, Biological and Bio-Engineering, NSF Engineering Research Center-Revolutionizing Metallic Biomaterials, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA. dzhu@ncat.edu.
North Carolina Agricultural and Technical State University · US

Funding

Brain Pericyte and Amyloid-beta Peptide InteractionSC2NS082475 · NINDS · NORTH CAROLINA AGRI & TECH ST UNIV · PI ZHU, DONGHUI · 2012 to 2014
$421k
NINDS NIH HHS SC2 NS082475NINDS NIH HHS SC2NS082475
6 · The paper itself

Abstract

Magnesium (Mg) alloys are promising scaffolds for the next generation of cardiovascular stents because of their better biocompatibility and biodegradation compared to traditional metals. However, insufficient mechanical strength and high degradation rate are still the two main limitations for Mg materials. Hydrofluoric acid (HF) treatment and collagen coating were used in this research to improve the endothelialization of two rare earth-based Mg alloys. Results demonstrated that a nanoporous film structure of fluoride with thickness of ~20 µm was formed on the Mg material surface, which improved the corrosion resistance. Primary human coronary artery endothelial cells (HCAECs) had much better attachment, spreading, growth and proliferation (the process of endothelialization) on HF-treated Mg materials compared to bare- or collagen-coated ones.

Indexed as

Biocompatible MaterialsStentsAlloysCell LineCell ProliferationCollagenCoronary VesselsEndothelial CellsFluoridesHumansHydrofluoric AcidMagnesiumMaterials TestingMetals, Rare EarthSurface PropertiesAlloysBiocompatible MaterialsCollagenFluoridesHydrofluoric AcidMagnesiumMetals, Rare Earth

Identifiers

PMID24670478
PMCPMC4013562
OpenAlexW1991506024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.