Evidence map›Paper›PMID 24669364›Full record

ReviewWorld journal of transplantation2014

ABO incompatible renal transplants: Good or bad?

Masaki Muramatsu, Hector Daniel Gonzalez, Roberto Cacciola, Atsushi Aikawa, Magdi M Yaqoob, Carmelo Puliatti

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Polyoma virus nephropathy in kidney transplantation.World journal of transplantation · 2017
    Review
  8. Fifteen-Year Analysis of Deceased Kidney Donation: A Single Transplant Center Experience in a Region of Northern Italy.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Renal transplantation in infants.Pediatric nephrology (Berlin, Germany) · 2016
    Review
  14. Article
  15. Article
  16. Article
  17. Immunoadsorption Column Reuse.Indian journal of nephrology
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Masaki MuramatsuMasaki Muramatsu, Magdi M Yaqoob, Carmelo Puliatti, Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Hector Daniel GonzalezMasaki Muramatsu, Magdi M Yaqoob, Carmelo Puliatti, Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Roberto CacciolaMasaki Muramatsu, Magdi M Yaqoob, Carmelo Puliatti, Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Atsushi AikawaMasaki Muramatsu, Magdi M Yaqoob, Carmelo Puliatti, Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Magdi M YaqoobMasaki Muramatsu, Magdi M Yaqoob, Carmelo Puliatti, Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Carmelo PuliattiMasaki Muramatsu, Magdi M Yaqoob, Carmelo Puliatti, Department of Translational Medicine and Therapeutics, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, United Kingdom.
Queen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ABO incompatible kidney transplantation (ABOi-KT) was previously considered to be an absolute contraindication for patients with end-stage kidney disease (ESKD) due to hyperacute rejection related to blood type barrier. Since the first successful series of ABOi-KT was reported, ABOi-KT is performed increasingly all over the world. ABOi-KT has led to an expanded donor pool and reduced the number of patients with ESKD awaiting deceased kidney transplantation (KT). Intensified immunosuppression and immunological understanding has helped to shape current desensitization protocols. Consequently, in recent years, ABOi-KT outcome is comparable to ABO compatible KT (ABOc-KT). However, many questions still remain unanswered. In ABOi-KT, there is an additional residual immunological risk that may lead to allograft damage, despite using current diverse but usually intensified immunosuppressive protocols at the expense of increasing risk of infection and possibly malignancy. Notably, in ABOi-KT, desensitization and antibody reduction therapies have increased the cost of KT. Reassuringly, there has been an evolution in ABOi-KT leading to a simplification of protocols over the last decade. This review provides an overview of the history, outcome, protocol, advantages and disadvantages in ABOi-KT, and focuses on whether ABOi-KT should be recommended as a therapeutic option of KT in the future.

Indexed as

ABO incompatibleAntibody depletionDesensitization protocolsImmunosuppressionKidney transplantationLiving donor transplantation

Identifiers

PMID24669364
PMCPMC3964193
OpenAlexW2084714829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.