ArticleImmunologic research2014
Global overview of primary immunodeficiencies: a report from Jeffrey Modell Centers worldwide focused on diagnosis, treatment, and discovery.
Article in Immunologic research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Prevalence of Ophthalmological Manifestations in Patients with Inborn Errors of Immunity: A Systematic Review and Meta-Analysis.Journal of clinical immunology · 2025Pooled it
- Cancer Trends in Inborn Errors of Immunity: A Systematic Review and Meta-Analysis.Journal of clinical immunology · 2024Pooled it
- Clinical and Immunological Features, Genetic Variants, and Outcomes of Patients with CD40 Deficiency.Journal of clinical immunology · 2023Pooled it
- Hyperimmunoglobulin syndromes: A review of HIGM, HIES, and HIDS.Journal of translational autoimmunity · 2025Review
- Selective Immunoglobulin A Deficiency Among Omani Patients Screened for Celiac Disease: A Cross-sectional Study.Oman medical journal · 2025Article
- Spectrum of different categories of Primary Immunodeficiency Disorders diagnosed at Children Hospital.Pakistan journal of medical sciences · 2025Article
- IgG antibody response to pneumococcal-conjugated vaccine (Prevenar®13) in children with immunodeficiency disorders.Medical microbiology and immunology · 2023Article
- Classification of common variable immunodeficiency through immunological and clinical phenotyping in Moroccan patients.Qatar medical journal · 2023Article
- Using a scenario approach to assess for the current and future demand of immunoglobulins: An interview and literature study from The Netherlands.Transfusion medicine (Oxford, England) · 2022Review
- Immune globulin therapy and kidney disease: Overview and screening, monitoring, and management recommendations.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2022Article
- Growth in diagnosis and treatment of primary immunodeficiency within the global Jeffrey Modell Centers Network.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022Article
- Diagnostic Barriers in Children with Immunodeficiencies in Central Asia: A Case-Based Discussion.Pediatric reports · 2021Article
- Consensus Middle East and North Africa Registry on Inborn Errors of Immunity.Journal of clinical immunology · 2021Article
- Immune cytopenias as a continuum in inborn errors of immunity: An in-depth clinical and immunological exploration.Immunity, inflammation and disease · 2021Article
- Systematic review of literature and analysis of big data from the National Health Insurance System on primary immunodeficiencies in Korea.Clinical and experimental pediatrics · 2021Article
- Efficacy and economics of targeted panel versus whole-exome sequencing in 878 patients with suspected primary immunodeficiency.The Journal of allergy and clinical immunology · 2021Article
- Innate Mechanisms in Selective IgA Deficiency.Frontiers in immunology · 2021Review
- Immunologic phenotype of a child with the MEHMO syndrome.Physiological research · 2020Article
- The spectrum of primary immunodeficiencies at a tertiary care hospital in Pakistan.The World Allergy Organization journal · 2020Article
- Patient experience with subcutaneous immunoglobulin 20%, Ig20Gly, for primary immunodeficiency diseases: a prespecified post hoc analysis of combined data from 2 pivotal trials.BMC immunology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary immunodeficiencies (PI) are defects of the immune system that cause severe infections if not diagnosed and treated appropriately. Many patients with PI are undiagnosed, under-diagnosed, or misdiagnosed. Over the last decade, the Jeffrey Modell Foundation has implemented a Physician Education and Public Awareness Campaign (PEPAC) to raise awareness, assure early diagnosis, appropriate treatment, and management, with the overall goal to reduce morbidities and mortalities related to PI. In order to evaluate the PEPAC program, data are requested annually from physician experts within the Jeffrey Modell Centers Network (JMCN). The JMCN, consisting of 556 expert physicians, at 234 academic institutions, in 196 cities, and 78 countries spanning six continents, provides the infrastructure for referral, diagnosis, and appropriate treatment for patients with PI. In addition, the JMCN has made a significant contribution to the field of immunology with the discovery of new genes at the centers. These advancements have led to an overall better understanding of the immune system and will continue to improve quality of life of those with PI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.