ArticleEuropean biophysics journal : EBJ2014
Membrane flickering of the human erythrocyte: physical and chemical effectors.
Article in European biophysics journal : EBJ, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Correlating nanoscale motion and ATP production in healthy and favism erythrocytes: a real-time nanomotion sensor study.Frontiers in microbiology · 2023Article
- Surface model of the human red blood cell simulating changes in membrane curvature under strain.Scientific reports · 2021Article
- Differential dielectroscopic data on the relation of erythrocyte membrane skeleton to erythrocyte deformability and flicker.European biophysics journal : EBJ · 2021Article
- Effect of hydrogen peroxide on normal and acatalasemic mouse erythrocytes.Toxicology reports · 2020Article
- Heat damage of cytoskeleton in erythrocytes increases membrane roughness and cell rigidity.Journal of biological physics · 2019Article
- Accelerating metabolism and transmembrane cation flux by distorting red blood cells.Science advances · 2017Article
- Membrane flickering of the human erythrocyte: constrained random walk used with Bayesian analysis.European biophysics journal : EBJ · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies suggest a link between adenosine triphosphate (ATP) concentration and the amplitude of cell membrane flickering (CMF) in the human erythrocyte (red blood cell; RBC). Potentially, the origin of this phenomenon and the unique discocyte shape could be active processes that account for some of the ATP turnover in the RBC. Active flickering could depend on several factors, including pH, osmolality, enzymatic rates and metabolic fluxes. In the present work, we applied the data analysis described in the previous article to study time courses of flickering RBCs acquired using differential interference contrast light microscopy in the presence of selected effectors. We also recorded images of air bubbles in aqueous detergent solutions and oil droplets in water, both of which showed rapid fluctuations in image intensity, the former showing the same type of spectral envelope (relative frequency composition) to RBCs. We conclude that CMF is not directly an active process, but that ATP affects the elastic properties of the membrane that flickers in response to molecular bombardment in a manner that is described mathematically by a constrained random walk.
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Registered trials
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