ArticlePsychopharmacology2014
Smoking improves divided attention in schizophrenia.
Article in Psychopharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Heritability of Neuropsychological Measures in Schizophrenia and Nonpsychiatric Populations: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2017Pooled it
- Smoking and its associations with metabolic indices, clinical symptoms, and cognitive functioning in schizophrenia.European archives of psychiatry and clinical neuroscience · 2026Article
- Sex differences in schizophrenia spectrum disorders: insights from the DiAPAson study using a data-driven approach.Social psychiatry and psychiatric epidemiology · 2025Article
- Smoking prevalence and correlates among inpatients with schizophrenia or schizoaffective disorder.Scientific reports · 2025Article
- Anticholinergic load: A commonly neglected and preventable risk to cognition during schizophrenia treatment?Schizophrenia research. Cognition · 2024Article
- Article
- Association of cigarette smoking with cognitive impairment in male patients with chronic schizophrenia.Psychopharmacology · 2020Article
- Unique Molecular Regulation of Higher-Order Prefrontal Cortical Circuits: Insights into the Neurobiology of Schizophrenia.ACS chemical neuroscience · 2018Review
- Neurobiological Determinants of Tobacco Smoking in Schizophrenia.Frontiers in psychiatry · 2018Review
- Nicotine dependence is associated with depression and childhood trauma in smokers with schizophrenia: results from the FACE-SZ dataset.European archives of psychiatry and clinical neuroscience · 2017Article
- Cannabis use and cognitive function in first episode psychosis: differential effect of heavy use.Psychopharmacology · 2016Article
- Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders.Annual review of pharmacology and toxicology · 2016Review
- California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS).Schizophrenia research · 2015Article
- Smoking in schizophrenic patients: A critique of the self-medication hypothesis.World journal of psychiatry · 2015Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleSmoking is highly prevalent in schizophrenia, and there is evidence for beneficial effects on neurocognition. Smoking is therefore hypothesized a self-medication in schizophrenia. Although much effort is devoted to characterize those cognitive domains that potentially benefit from smoking, divided attention has not yet been investigated.
objectivesThe aim of this study was to analyze the interactional effects of diagnosis of schizophrenia and smoking history on divided attention.
methodsWe investigated behavioral measures of divided attention in a sample of 48 schizophrenic patients and 48 controls (24 current smokers and non-smokers each) carefully matched for age, sex, education, verbal IQ, and smoking status with general linear models.
resultsMost important within the scope of this study, significant interactions were found for valid reactions and errors of omission: Performance substantially increased in smoking schizophrenic patients, but not in controls. Further, these interactions were modified by sex, driven by female schizophrenic patients who showed a significant behavioral advantage of smokers over non-smokers, other than male schizophrenic patients or healthy controls who did not express this sex-specific pattern.
conclusionsResults suggest a positive effect of smoking history on divided attention in schizophrenic patients. This study provides first evidence that the complex attention domain of divided attention is improved by smoking, which further substantiates the self-medication hypothesis of smoking in schizophrenia, although this has been shown mainly for sustained and selective attention. Gender-specific effects on cognition need to be further investigated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.