Trial reportJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2014
Ultrafast Doppler reveals the mapping of cerebral vascular resistivity in neonates.
Trial report in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- In Vivo Wide-Field Mapping of Microvascular Dynamics in Orthotopic GL261 Gliomas by Super-Resolution Ultrasound Imaging.Annals of biomedical engineering · 2026Article
- Microvascular ultrasound imaging of the neonatal brain: a scoping review.European journal of pediatrics · 2026Article
- Ultrafast ultrasound imaging reveals altered cerebral blood flow in newborn rats with hypoxic-ischemic encephalopathy.Pediatric research · 2026Article
- Functional ultrasound imaging in preclinical brain stimulation: from multimodal readouts to closed-loop neuromodulation.Frontiers in neuroscience · 2026Review
- 3D multiparametric ultrasound imaging of steatotic liver disease in a study with male rats.Nature communications · 2025Article
- Cerebral resistive indices and intraventricular hemorrhage in premature neonates < 29 weeks' gestation: a pilot prospective cohort study.BMC pediatrics · 2025Article
- Monitoring microvascular changes over time with a repositionable 3D ultrasonic capacitive micromachined row-column sensor.Science advances · 2025Article
- Ultrasound-based quantitative microvasculature imaging for early prediction of response to neoadjuvant chemotherapy in patients with breast cancer.Breast cancer research : BCR · 2025Article
- Correlations between ultrafast power Doppler perfusion imaging variables and clinical disease activity in rheumatoid arthritis: potential applications for diagnosing and treating patients in deep clinical remission.Ultrasonography (Seoul, Korea) · 2024Article
- Quantification of brain-wide vascular resistivity via ultrafast Doppler in human neonates helps early detection of white matter injury.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Contrast Agent-Free 3D Renal Ultrafast Doppler Imaging Reveals Vascular Dysfunction in Acute and Diabetic Kidney Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- A Transverse Velocity Spectral Estimation Method for Ultrafast Ultrasound Doppler Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Superharmonic and Microultrasound Imaging With Plane Wave Beamforming Techniques.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Navigating the Complexities of Intraventricular Hemorrhage in Preterm Infants: An Updated Review.Cureus · 2023Review
- Adaptation of Range-Doppler Algorithm for Efficient Beamforming of Monostatic and Multistatic Ultrasound Signals.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Real-Time In Vivo Imaging of Human Liver Vasculature Using Coherent Flow Power Doppler: A Pilot Clinical Study.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Quantitative assessment of ensemble coherency in contrast-free ultrasound microvasculature imaging.Medical physics · 2021Article
- Precision Medicine in Neonates: A Tailored Approach to Neonatal Brain Injury.Frontiers in pediatrics · 2021Review
- Feasibility of Doppler Ultrasound for Cortical Cerebral Blood Flow Velocity Monitoring During Major Non-cardiac Surgery of Newborns.Frontiers in pediatrics · 2021Article
- Blood Flow Imaging in the Neonatal Brain Using Angular Coherence Power Doppler.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In vivo mapping of the full vasculature dynamics based on Ultrafast Doppler is showed noninvasively in the challenging case of the neonatal brain. Contrary to conventional pulsed-wave (PW) Doppler Ultrasound limited for >40 years to the estimation of vascular indices at a single location, the ultrafast frame rate (5,000 Hz) obtained using plane-wave transmissions leads to simultaneous estimation of full Doppler spectra in all pixels of wide field-of-view images within a single cardiac cycle and high sensitivity Doppler imaging. Consequently, 2D quantitative maps of the cerebro-vascular resistivity index (RI) are processed and found in agreement with local measurements obtained on large arteries of healthy neonates using conventional PW Doppler. Changes in 2D resistivity maps are monitored during recovery after therapeutic whole-body cooling of full-term neonates treated for hypoxic ischemic encephalopathy. Arterial and venous vessels are unambiguously differentiated on the basis of their distinct hemodynamics. The high spatial (250 × 250 μm(2)) and temporal resolution (<1 ms) of Ultrafast Doppler imaging combined with deep tissue penetration enable precise quantitative mapping of deep brain vascular dynamics and RI, which is far beyond the capabilities of any other imaging modality.
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