ArticleEuropean journal of human genetics : EJHG2014
Y-chromosome E haplogroups: their distribution and implication to the origin of Afro-Asiatic languages and pastoralism.
Article in European journal of human genetics : EJHG, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 55 citations in OpenAlex.
- The episode of genetic drift defining the migration of humans out of Africa is derived from a large east African population size.PloS one · 2014Trial
- Operationalizing language-based population stratification for widening access to precision genomics in Africa.Frontiers in public health · 2025Article
- Incidence, Phenotypes, and Genotypes of Neonatal Diabetes: A 16-Year Experience. The Rare Genetic Etiologies of Neonatal Diabetes Are Common in Sudan.Pediatric diabetes · 2024Article
- Genetic diversity of the Sudanese: insights on origin and implications for health.Human molecular genetics · 2021Review
- African genetic diversity provides novel insights into evolutionary history and local adaptations.Human molecular genetics · 2018Review
- Phylogeographic Refinement and Large Scale Genotyping of Human Y Chromosome Haplogroup E Provide New Insights into the Dispersal of Early Pastoralists in the African Continent.Genome biology and evolution · 2015Article
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2 authors at 1 institution in 1 country.
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Abstract
Archeological and paleontological evidences point to East Africa as the likely area of early evolution of modern humans. Genetic studies also indicate that populations from the region often contain, but not exclusively, representatives of the more basal clades of mitochondrial and Y-chromosome phylogenies. Most Y-chromosome haplogroup diversity in Africa, however, is present within macrohaplogroup E that seem to have appeared 21 000-32 000 YBP somewhere between the Red Sea and Lake Chad. The combined analysis of 17 bi-allelic markers in 1214 Y chromosomes together with cultural background of 49 populations displayed in various metrics: network, multidimensional scaling, principal component analysis and neighbor-joining plots, indicate a major contribution of East African populations to the foundation of the macrohaplogroup, suggesting a diversification that predates the appearance of some cultural traits and the subsequent expansion that is more associated with the cultural and linguistic diversity witnessed today. The proto-Afro-Asiatic group carrying the E-P2 mutation may have appeared at this point in time and subsequently gave rise to the different major population groups including current speakers of the Afro-Asiatic languages and pastoralist populations.
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