ReviewEnvironmental health perspectives2014
Controlled exposures to air pollutants and risk of cardiac arrhythmia.
Review in Environmental health perspectives, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 48 citations in OpenAlex.
- Cardiac electrophysiological responses to traffic pollution in adults with or without chronic cardiopulmonary diseases.Environment international · 2025Article
- Controlled human exposures: a review and comparison of the health effects of diesel exhaust and wood smoke.Particle and fibre toxicology · 2024Review
- HIPTox-Hazard Identification Platform to Assess the Health Impacts from Indoor and Outdoor Air Pollutant Exposures, through Mechanistic Toxicology: A Single-Centre Double-Blind Human Exposure Trial Protocol.International journal of environmental research and public health · 2024Article
- Environmental Stressors and the PINE Network: Can Physical Environmental Stressors Drive Long-Term Physical and Mental Health Risks?International journal of environmental research and public health · 2022Review
- Controlled human exposure to diesel exhaust: a method for understanding health effects of traffic-related air pollution.Particle and fibre toxicology · 2022Review
- Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions.Particle and fibre toxicology · 2022Review
- The Influence of Environmental Air Pollution on Ventricular Arrhythmias: A Scoping Review.Current cardiology reviews · 2022Article
- Daily Exposure to Air Pollution Particulate Matter Is Associated with Atrial Fibrillation in High-Risk Patients.International journal of environmental research and public health · 2020Article
- Do acute changes in ambient air pollution increase the risk of potentially fatal cardiac arrhythmias in patients with implantable cardioverter defibrillators?Environmental health : a global access science source · 2020Article
- Air pollutants and outpatient visits for cardiovascular disease in a severe haze-fog city: Shijiazhuang, China.BMC public health · 2019Article
- Amiodarone and acupuncture for cardiac arrhythmia: Study protocol for a systematic review.Medicine · 2019Article
- The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges.Frontiers in pharmacology · 2019Review
- Fine and Coarse Particulate Matter Exposures and Associations with Acute Cardiac Events among Participants in a Telemedicine Service: A Case-Crossover Study.Environmental health perspectives · 2018Article
- Health benefits of PMInternational journal of biometeorology · 2017Article
- Multicenter Ozone Study in oldEr Subjects (MOSES): Part 1. Effects of Exposure to Low Concentrations of Ozone on Respiratory and Cardiovascular Outcomes.Research report (Health Effects Institute) · 2017Article
- Biomass Burning as a Source of Ambient Fine Particulate Air Pollution and Acute Myocardial Infarction.Epidemiology (Cambridge, Mass.) · 2017Article
- Diesel Exhaust Worsens Cardiac Conduction Instability in Dobutamine-Challenged Wistar-Kyoto and Spontaneously Hypertensive Rats.Cardiovascular toxicology · 2017Article
- Haze is a risk factor contributing to the rapid spread of respiratory syncytial virus in children.Environmental science and pollution research international · 2016Article
- Xenobiotic pulmonary exposure and systemic cardiovascular response via neurological links.American journal of physiology. Heart and circulatory physiology · 2015Review
- Environmental factors in cardiovascular disease.Nature reviews. Cardiology · 2015Review
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundEpidemiological studies have reported associations between air pollution exposure and increases in cardiovascular morbidity and mortality. Exposure to air pollutants can influence cardiac autonomic tone and reduce heart rate variability, and may increase the risk of cardiac arrhythmias, particularly in susceptible patient groups.
objectivesWe investigated the incidence of cardiac arrhythmias during and after controlled exposure to air pollutants in healthy volunteers and patients with coronary heart disease.
methodsWe analyzed data from 13 double-blind randomized crossover studies including 282 participants (140 healthy volunteers and 142 patients with stable coronary heart disease) from whom continuous electrocardiograms were available. The incidence of cardiac arrhythmias was recorded for each exposure and study population.
resultsThere were no increases in any cardiac arrhythmia during or after exposure to dilute diesel exhaust, wood smoke, ozone, concentrated ambient particles, engineered carbon nanoparticles, or high ambient levels of air pollution in either healthy volunteers or patients with coronary heart disease.
conclusionsAcute controlled exposure to air pollutants did not increase the short-term risk of arrhythmia in participants. Research employing these techniques remains crucial in identifying the important pathophysiological pathways involved in the adverse effects of air pollution, and is vital to inform environmental and public health policy decisions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.