Evidence map›Paper›PMID 24667132›Full record

Trial reportNutrients2014

Selenium fortification of an Italian rice cultivar via foliar fertilization with sodium selenate and its effects on human serum selenium levels and on erythrocyte glutathione peroxidase activity.

Attilio Giacosa, Milena Anna Faliva, Simone Perna, Claudio Minoia, Anna Ronchi, Mariangela Rondanelli

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Arsenic exposure and increasedRedox biochemistry and chemistry · 2023
    Article
  5. Review
  6. The Role of Selenium in Pathologies: An Updated Review.Antioxidants (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Article
  9. Tuning of the Amount of Se in Rice (Molecules (Basel, Switzerland) · 2020
    Article
  10. Article
  11. Review
  12. Selenium and Sulfur to Produce Allium Functional Crops.Molecules (Basel, Switzerland) · 2017
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Attilio GiacosaDepartment of Gastroenterology, Policlinico di Monza, Monza 20900, Italy. attilio.giacosa@policlinicodimonza.it.
Milena Anna FalivaDepartment of Applied Health Sciences, Azienda di Servizi alla Persona (ASP) di Pavia, University of Pavia, Pavia 27100, Italy. milo.milena87@hotmail.it.
Simone PernaDepartment of Applied Health Sciences, Azienda di Servizi alla Persona (ASP) di Pavia, University of Pavia, Pavia 27100, Italy. simoneperna@hotmail.it.
Claudio MinoiaLaboratorio di Misure Ambientali e Tossicologiche, Fondazione S. Maugeri, Istituto Scientifico di Pavia, Pavia 27100, Italy. claudio.minoia@fsm.it.
Anna RonchiLaboratorio di Misure Ambientali e Tossicologiche, Fondazione S. Maugeri, Istituto Scientifico di Pavia, Pavia 27100, Italy. anna.ronchi@fsm.it.
Mariangela RondanelliDepartment of Applied Health Sciences, Azienda di Servizi alla Persona (ASP) di Pavia, University of Pavia, Pavia 27100, Italy. mariangela.rondanelli@unipv.it.
Azienda di Servizi alla Persona di Pavia (Italy) · ITFondazione Salvatore Maugeri · ITFondazione Lanza · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selenium food fortification could be a cost-effective strategy to counteract the inadequacy of selenium intake among the Italian population. In this study, the effect of foliar fertilization with sodium selenate of an Italian rice cultivar and the increase of serum selenium and of erythrocyte glutathione peroxidase (GPx) activity after intake of fortified rice, have been evaluated. The effect of foliar fertilization with sodium selenate (50 g Se/ha) vs. water was studied. Moreover, in a randomized, double-blind study, 10 healthy women supplemented their usual diet with a daily dose of 80 g of Se-enriched-rice and 10 matched-women with 80 g of regular rice. Before, after 5 and 20 days of supplementation, serum Se and GPx-activity were evaluated. The mean selenium content in Se-enriched-rice was 1.64 ± 0.28 μg/g, while in regular rice it was 0.36 ± 0.15 μg/g (p < 0.001). A significant increase of serum Se and GPx-activity was observed only in the intervention group and only after 20 days. The results show that selenium fortification of rice can be achieved with foliar fertilization with sodium selenate and that the 20 days intake of this Se-enriched-rice increases the serum selenium levels and GPx-activity.

Indexed as

Dietary SupplementsFood, FortifiedAdultBody Mass IndexDietDouble-Blind MethodErythrocytesFemaleGlutathione PeroxidaseHumansItalyLinear ModelsOryzaSelenic AcidSeleniumYoung AdultGlutathione PeroxidaseSelenic AcidSelenium

Identifiers

PMID24667132
PMCPMC3967191
OpenAlexW2077109440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.