Evidence map›Paper›PMID 24667065›Full record

ArticleParasites & vectors2014

First report of Babesia gibsoni in Central America and survey for vector-borne infections in dogs from Nicaragua.

Lanjing Wei, Patrick Kelly, Kate Ackerson, Jilei Zhang, Heba S El-Mahallawy, Bernhard Kaltenboeck, Chengming Wang

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Canine Babesiosis Caused by LargeAnimals : an open access journal from MDPI · 2023
    Review
  4. Review
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  7. Article
  8. Review
  9. Article
  10. Article
  11. A review of the genusResearch and reports in tropical medicine · 2018
    Review
  12. Article
  13. Article
  14. Article
  15. Current tropical medicine reports
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Lanjing Wei
Patrick Kelly
Kate Ackerson
Jilei Zhang
Heba S El-Mahallawy
Bernhard Kaltenboeck
Chengming WangYangzhou University College of Veterinary Medicine, Yangzhou, Jiangsu, P, R, China. chengmingwang@gmail.com.
Yangzhou University · CNRoss University School of Veterinary Medicine · KNAuburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough many vector-borne diseases are important causes of morbidity and mortality in dogs in tropical areas and potential zoonoses, there is little information on these conditions in Central America.

methodsSeven qPCRs for vector-borne pathogens were performed on a Roche LightCycler PCR Instrument to investigate their prevalence in a convenience sample of whole blood samples from apparently healthy dogs in Nicaragua. Also, a qPCR targeting the canine hydroxymethylbilane synthase (HMBS) gene was used as an endogenous internal control and verified the quality and quantity of DNA in the samples was appropriate for the study.

resultsWe found DNA of Rickettsia felis (5%), Babesia spp. (26%), Hepatozoon canis (51%), Anaplasma platys (13%) and Ehrlichia canis (56%) in the 39 dogs studied. The qPCRs for Coxiella burnetii and Dirofilaria immitis were negative. Of the 30 (80%) dogs that were positive by qPCR, 12 (31%) were positive for one agent, 11 (28%) for two, 3 (8%) for three, and 4 (10%) for four agents.

conclusionsThis is the first report of B. gibsoni in dogs from Central America and the first recording of vector-borne agents in dogs from Nicaragua. Dogs in Nicaragua are commonly infected with a variety of vector-borne pathogens, some of which may also infect people.

Indexed as

AnaplasmaAnimalsBabesiaBabesiosisDNA, ProtozoanDog DiseasesDogsEhrlichiaEucoccidiidaGene DosageHydroxymethylbilane SynthaseNicaraguaPolymerase Chain ReactionPrevalenceProtozoan ProteinsRickettsiaDNA, ProtozoanHydroxymethylbilane SynthaseProtozoan Proteins

Identifiers

PMID24667065
PMCPMC3987057
OpenAlexW2163538124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.