SynthesisReproductive biology and endocrinology : RB&E2014
Serum AMH level as a marker of acute and long-term effects of chemotherapy on the ovarian follicular content: a systematic review.
Synthesis in Reproductive biology and endocrinology : RB&E, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predicting Ovarian Activity in Women Affected by Early Breast Cancer: A Meta-Analysis-Based Nomogram.The oncologist · 2015Pooled it
- Hydroxycarbamide exposure and ovarian reserve in women with sickle cell disease in the Multicenter Study of Hydroxycarbamide.British journal of haematology · 2020Trial
- [Female reproductive function -after radioiodine therapy for differentiated thyroid carcinoma].Problemy endokrinologii · 2025Article
- Prostate Cancer Treatments and Their Effects on Male Fertility: Mechanisms and Mitigation Strategies.Journal of personalized medicine · 2025Review
- Age and serum anti-Müllerian hormone levels as predictors of time to return of menses after chemotherapy.Reproduction & fertility · 2025Article
- Folliculogenesis resumption after ovarian cortex transplantation: what is the earliest hormonal indicator?Archives of gynecology and obstetrics · 2024Article
- Fertility Potential and Gonadal Function in Survivors of Reduced-Intensity Hematopoietic Stem Cell Transplantation.Transplantation and cellular therapy · 2024Article
- Female cancer survivors: sexual function, psychological distress, and remaining fertility.Journal of assisted reproduction and genetics · 2024Article
- Impact of Systemic Therapy on Fertility in Women with Early-Stage Breast Cancer.Current breast cancer reports · 2024Article
- A New Model Including AMH Cut-off Levels to Predict Post-treatment Ovarian Function in Early Breast Cancer: A Prospective Cohort Study.Archives of Iranian medicine · 2024Article
- Zuogui and Yougui pills improve perimenopausal syndrome regulation of apoptosis in mice.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- Fertility Preservation in Young Women With Breast Cancer: A Review.Journal of breast cancer · 2023Review
- VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy.Current cancer drug targets · 2023Article
- Anti-Müllerian hormone beyond an ovarian reserve marker: the relationship with the physiology and pathology in the life-long follicle development.Frontiers in endocrinology · 2023Review
- Anti-Müllerian hormone levels and breast cancer risk in the study of women's health across the nation.Cancer causes & control : CCC · 2022Article
- Fertility after Curative Therapy for Sickle Cell Disease: A Comprehensive Review to Guide Care.Journal of clinical medicine · 2022Review
- Evidence of cancer therapy-induced chronic inflammation in the ovary across multiple species: A potential cause of persistent tissue damage and follicle depletion.Journal of reproductive immunology · 2022Article
- After cyclophosphamide exposure, granulosa cells recover their anti-müllerian hormone-producing ability but not their numbers.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021Article
- Molecular Mechanism and Prevention Strategy of Chemotherapy- and Radiotherapy-Induced Ovarian Damage.International journal of molecular sciences · 2021Review
- The role of gonadotropin-releasing hormone agonists in female fertility preservation.Clinical and experimental reproductive medicine · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anti-Müllerian hormone (AMH) is a very sensitive indicator of the ovarian follicular content. Chemotherapeutic agents are notoriously ovariotoxic in that they damage follicles. The aim of this systematic review was to investigate the interest of serum AMH variations in determining the acute and long-term effects of chemotherapy on the ovarian reserve. According to the PRISMA guidelines, searches were conducted on PubMed for all English language articles until December 2013. Fifteen articles that focused on dynamic variations of AMH levels before and after chemotherapy were selected. Cancer patients have significantly lower AMH after chemotherapy than age-matched controls. Longitudinal studies of AMH variations before, during and after chemotherapy provide information about the degree of follicle loss for each patient according to different chemotherapy regimens. Different patterns of AMH levels during the ovarian recovery phase make it possible to discriminate between high and low gonadotoxic chemotherapy protocols. In addition, pretreatment AMH levels are shown to predict the long-term ovarian function after the end of treatment. These results may help to better understand the ovarian toxicity mechanisms of chemotherapy and to predict the degree of the ovarian follicle loss. Therefore, it can be useful for fertility preservation strategies, fertility counseling and future family planning.
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