Evidence map›Paper›PMID 24665239›Full record

ArticleSaudi journal of anaesthesia2014

Ring block with levobupivacaine 0.25% and paracetamol vs. paracetamol alone in children submitted to three different surgical techniques of circumcision: A prospective randomized study.

Nick Zavras, Stella Tsamoudaki, Efstratios Christianakis, Demetrios Schizas, Emmanuel Pikoulis, Helen Kyritsi, George Chrousos

Open access · diamondAbstract read
In one paragraph

Article in Saudi journal of anaesthesia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Evaluating Caudal Block Enhancements in Pediatric Circumcision: Do Additional Analgesics Make a Difference?Medical science monitor : international medical journal of experimental and clinical research · 2023
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Nick ZavrasDepartment of Surgery, ATTIKO University Hospital, Athens-Greece.
Stella TsamoudakiDepartment of Pediatric Surgery, Penteli, General Children's Hospital, P. Penteli, Athens-Greece.
Efstratios ChristianakisDepartment of Pediatric Surgery, Penteli, General Children's Hospital, P. Penteli, Athens-Greece.
Demetrios SchizasDepartment of Surgery, ATTIKO University Hospital, Athens-Greece.
Emmanuel PikoulisDepartment of Surgery, Laiko University Hospital, Athens-Greece.
Helen KyritsiDepartment of Nursing A, Technological and Educational Institute of Athens-Greece.
George ChrousosDepartment of Pediatrics, Athens University Medical School, Aghia Sophia Children's Hospital, Athens-Greece.
Penteli General Children's Hospital · GRUniversity General Hospital Attikon · GRChildren's Hospital Agia Sophia · GRLaiko General Hospital of Athens · GRTechnological Educational Institute of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundcircumcision in children is a painful procedure. We aim compare the intraoperative and postoperative efficacy of three different surgical procedures of the ring block using levobupivacaine 0.25% combined with rectal paracetamol as opposed to rectal paracetamol alone.

methodsthe study included 106 boys scheduled to undergo circumcision. The patients were randomly assigned within two groups to receive either ring block with levobupivacaine 0.25% and rectal paracetamol 30 mg/kg, or rectal paracetamol 30 mg/kg alone. The following surgical procedures were performed: sutureless proctoplasty, preputial plasty, and conventional circumcision. The efficacy of intraoperative analgesia was estimated on the basis of increases in heart rate and mean arterial pressure. Postoperatively, children were assessed for pain, pain-free (PF) period, and the total doses of analgesics administered during hospitalization, on the day after discharge, and on the first and second postoperative days.

resultsall children remained stable during anesthesia. Postoperatively, the mean pain score did not show statistical differences between the groups. Children who received combined analgesia had a longer PF period (P < 0.001). However, the total doses of paracetamol administered during the observational period showed no differences. Children undergoing sutureless prepuceplasty received lower doses of paracetamol postoperatively (P < 0.001).

conclusionsubcutaneous ring block either with levobupivacaine 0.25% plus rectal paracetamol or rectal paracetamol alone provides adequate intraoperative and postoperative analgesia in circumcised children. However, combined analgesia allows a longer PF period. The need for less analgesic administration in children undergoing sutureless prepuceplasty could mean that the circumcision techniques might be a mitigating factor in terms of pain.

Indexed as

Circumcisionlevobupivacaineparacetamol

Identifiers

PMID24665239
PMCPMC3950452
OpenAlexW2139771236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.