ArticleThe Journal of physiology2014
Synaptic communication and signal processing among sensory cells in taste buds.
Article in The Journal of physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed.
- Variability in P2X receptor composition in human taste nerves: implications for treatment of chronic cough.ERJ open research · 2023Article
- Neuronal Compartmentalization: A Means to Integrate Sensory Input at the Earliest Stage of Information Processing?BioEssays : news and reviews in molecular, cellular and developmental biology · 2020Article
- Electrophysiological Responses from the Human Tongue to the Six Taste Qualities and Their Relationships with PROP Taster Status.Nutrients · 2020Article
- Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals.Chemical senses · 2019Review
- The ATP-P2X7 Signaling Pathway Participates in the Regulation of Slit1 Expression in Satellite Glial Cells.Frontiers in cellular neuroscience · 2019Article
- Review
- CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.Neuron · 2018Article
- ATP Release Channels.International journal of molecular sciences · 2018Review
- Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin.Frontiers in cellular neuroscience · 2018Article
- Type III Cells in Anterior Taste Fields Are More Immunohistochemically Diverse Than Those of Posterior Taste Fields in Mice.Chemical senses · 2017Article
- Taste buds: cells, signals and synapses.Nature reviews. Neuroscience · 2017Review
- Glutamate: Tastant and Neuromodulator in Taste Buds.Advances in nutrition (Bethesda, Md.) · 2016Review
- Expression of calcium-activated chloride channels Ano1 and Ano2 in mouse taste cells.Pflugers Archiv : European journal of physiology · 2016Article
- Progress and renewal in gustation: new insights into taste bud development.Development (Cambridge, England) · 2015Review
- Breadth of tuning in taste afferent neurons varies with stimulus strength.Nature communications · 2015Article
- Leptin's effect on taste bud calcium responses and transmitter secretion.Chemical senses · 2015Article
- Molecular mechanisms of taste recognition: considerations about the role of saliva.International journal of molecular sciences · 2015Review
- Intravital microscopic interrogation of peripheral taste sensation.Scientific reports · 2015Article
- The taste of table salt.Pflugers Archiv : European journal of physiology · 2015Review
- Sensory end-organs: signal processing in the periphery: a symposium presented at the 2013 Annual Meeting of the Society for Neuroscience, San Diego, CA, USA.The Journal of physiology · 2014Article
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Authors and funding
1 author.
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Abstract
Taste buds (sensory structures embedded in oral epithelium) show a remarkable diversity of transmitters synthesized and secreted locally. The known transmitters accumulate in a cell type selective manner, with 5-HT and noradrenaline being limited to presynaptic cells, GABA being synthesized in both presynaptic and glial-like cells, and acetylcholine and ATP used for signalling by receptor cells. Each of these transmitters participates in local negative or positive feedback circuits that target particular cell types. Overall, the role of ATP is the best elucidated. ATP serves as a principal afferent transmitter, and also is the key trigger for autocrine positive feedback and paracrine circuits that result in potentiation (via adenosine) or inhibition (via GABA or 5-HT). While many of the cellular receptors and mechanisms for these circuits are known, their impact on sensory detection and perception remains to be elaborated in most instances. This brief review examines what is known, and some of the open questions and controversies surrounding the transmitters and circuits of the taste periphery.
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Registered trials
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