ArticleJournal of materials science. Materials in medicine2014
Comparative performance of collagen nanofibers electrospun from different solvents and stabilized by different crosslinkers.
Article in Journal of materials science. Materials in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 75 citations in OpenAlex.
- Effect of temperature on bighead carp (Food chemistry: X · 2025Article
- Chemical Crosslinking of Acid Soluble Collagen Fibres.Biomimetics (Basel, Switzerland) · 2025Review
- Fabrication and characterisation of collagen/pullulan ultra-thin fibers by electrospinning.Food chemistry: X · 2024Article
- Effects of solvent conditions on the self-assembly of heterotrimeric collagen-like peptide (CLP) triple helices: a coarse-grained simulation study.Soft matter · 2023Article
- Electrospun Collagen Scaffold Bio-Functionalized with Recombinant ICOS-Fc: An Advanced Approach to Promote Bone Remodelling.Polymers · 2022Article
- 3D printed devices with integrated collagen scaffolds for cell culture studies including transepithelial/transendothelial electrical resistance (TEER) measurements.Analytica chimica acta · 2022Article
- Effect of Olibanum Extract/Graphene Oxide on Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-Like Cells on Freeze Dried Scaffolds.Iranian journal of biotechnology · 2022Article
- 3D Cell Culture Systems: Tumor Application, Advantages, and Disadvantages.International journal of molecular sciences · 2021Review
- Biomimetic Scaffolds Obtained by Electrospinning of Collagen-Based Materials: Strategies to Hinder the Protein Denaturation.Materials (Basel, Switzerland) · 2021Article
- Crosslinking of Gelatin in Bicomponent Electrospun Fibers.Materials (Basel, Switzerland) · 2021Article
- Nanofibrous Gelatin-Based Biomaterial with Improved Biomimicry Using D-Periodic Self-Assembled Atelocollagen.Biomimetics (Basel, Switzerland) · 2021Article
- Collagen-Based Electrospun Materials for Tissue Engineering: A Systematic Review.Bioengineering (Basel, Switzerland) · 2021Review
- Cross-Linking Optimization for Electrospun Gelatin: Challenge of Preserving Fiber Topography.Polymers · 2020Article
- Preparation and Characterization of Electrospun Collagen Based Composites for Biomedical Applications.Materials (Basel, Switzerland) · 2020Article
- Microfabrication of a biomimetic arcade-like electrospun scaffold for cartilage tissue engineering applications.Journal of materials science. Materials in medicine · 2020Article
- Core-Shell Nanofibrous Scaffolds for Repair of Meniscus Tears.Tissue engineering. Part A · 2019Article
- New Strategy to Cope with Common Fishery Policy Landing Obligation: Collagen Extraction from Skins and Bones of Undersized Hake (Polymers · 2019Article
- Tendon Fascicle-Inspired Nanofibrous Scaffold of Polylactic acid/Collagen with Enhanced 3D-Structure and Biomechanical Properties.Scientific reports · 2018Article
- Random laser imaging of bovine pericardium under the uniaxial tensile test.Biomedical optics express · 2018Article
- Mechanically Reinforced Extracellular Matrix Scaffold for Application of Cartilage Tissue Engineering.Tissue engineering and regenerative medicine · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Collagen electrospun scaffolds well reproduce the structure of the extracellular matrix (ECM) of natural tissues by coupling high biomimetism of the biological material with the fibrous morphology of the protein. Structural properties of collagen electrospun fibers are still a debated subject and there are conflicting reports in the literature addressing the presence of ultrastructure of collagen in electrospun fibers. In this work collagen type I was successfully electrospun from two different solvents, trifluoroethanol (TFE) and dilute acetic acid (AcOH). Characterization of collagen fibers was performed by means of SEM, ATR-IR, Circular Dichroism and WAXD. We demonstrated that collagen fibers contained a very low amount of triple helix with respect to pristine collagen (18 and 16% in fibers electrospun from AcOH and TFE, respectively) and that triple helix denaturation occurred during polymer dissolution. Collagen scaffolds were crosslinked by using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), a commonly employed crosslinker for electrospun collagen, and 1,4-butanediol diglycidyl ether (BDDGE), that was tested for the first time in this work as crosslinking agent for collagen in the form of electrospun fibers. We demonstrated that BDDGE successfully crosslinked collagen and preserved at the same time the scaffold fibrous morphology, while scaffolds crosslinked with EDC completely lost their porous structure. Mesenchymal stem cell experiments demonstrated that collagen scaffolds crosslinked with BDDGE are biocompatible and support cell attachment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.