Evidence map›Paper›PMID 24664305›Full record

ReviewInternational journal of clinical oncology2014

Update of molecular pathobiology in oral cancer: a review.

Tomonori Sasahira, Tadaaki Kirita, Hiroki Kuniyasu

Abstract readReview
PubMed Publisher
In one paragraph

Review in International journal of clinical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 90 citations in OpenAlex.

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  18. Prognostic value of theArchives of medical science : AMS · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tomonori SasahiraDepartment of Molecular Pathology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8521, Japan, sasa@naramed-u.ac.jp.
Tadaaki Kirita
Hiroki Kuniyasu
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer including oral squamous cell carcinoma (OSCC) is the sixth most common cancer in the world. OSCC has a high potential for local invasion and nodal metastasis, and the overall 5-year survival rate has not significantly changed during the past 30 years. Recent research has elucidated the detailed molecular mechanisms of carcinogenesis, tumor progression, and metastasis of OSCC. It is generally accepted that OSCC arises from multiple genetic alterations caused by chronic exposure to carcinogens such as alcohol, smoking, viral infections, and inflammation. The molecular mechanisms of carcinogenesis, tumor progression, and metastasis of head and neck cancer have been elucidated by recent advances in molecular biology. However, many unsolved questions remain. In this review, we describe the current molecular biological findings such as human papillomavirus infection, epithelial-mesenchymal transition, microRNA, and our novel molecular pathological findings of OSCC.

Indexed as

Carcinoma, Squamous CellEpithelial-Mesenchymal TransitionExtracellular Matrix ProteinsGene Expression Regulation, NeoplasticHMGB1 ProteinHumansMicroRNAsMolecular Targeted TherapyMouth NeoplasmsNeoplasm ProteinsOncogene ProteinsPapillomavirus InfectionsReceptor for Advanced Glycation End ProductsExtracellular Matrix ProteinsHMGB1 ProteinHMGB1 protein, humanMIA protein, humanMicroRNAsNeoplasm ProteinsOncogene Proteinsoncogene protein trkReceptor for Advanced Glycation End Products

Identifiers

PMID24664305
OpenAlexW1992423599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.