Evidence map›Paper›PMID 24663954›Full record

ArticleJournal of human lactation : official journal of International Lactation Consultant Association2014

Cytokines, Chemokines, and Growth Factors in Banked Human Donor Milk for Preterm Infants.

Maureen Groer, Allyson Duffy, Shannon Morse, Bradley Kane, Judy Zaritt, Shari Roberts, Terri Ashmeade

Open access · greenAbstract read
In one paragraph

Article in Journal of human lactation : official journal of International Lactation Consultant Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Inflammatory Markers in Mother's Own Milk and Infant Stool of Very Low Birthweight Infants.Journal of human lactation : official journal of International Lactation Consultant Association · 2023
    Trial
  2. Exclusive human milk diet reduces incidence of severe intraventricular hemorrhage in extremely low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Observational
  3. Article
  4. Article
  5. Pasteurization Preserves IL-8 in Human Milk.Frontiers in pediatrics · 2018
    Article
  6. Article
  7. Effect of Promoter Polymorphisms on Cytokine Concentration in Preterm Breast Milk and Subsequent Infant Outcomes.Journal of human lactation : official journal of International Lactation Consultant Association · 2016
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maureen GroerUniversity of South Florida College of Nursing, Tampa, FL, USA mgroer@health.usf.edu.
Allyson DuffyUniversity of South Florida College of Nursing, Tampa, FL, USA.
Shannon MorseUniversity of South Florida College of Nursing, Tampa, FL, USA.
Bradley KaneUniversity of South Florida College of Nursing, Tampa, FL, USA.
Judy ZarittUniversity of South Florida College of Medicine, Tampa, FL, USA.
Shari RobertsUniversity of South Florida College of Medicine, Tampa, FL, USA.
Terri AshmeadeUniversity of South Florida College of Medicine, Tampa, FL, USA.
Florida College · USUniversity of South Florida · US

Funding

The association between preterm milk immunobiology and infant healthR21NR013094 · NINR · UNIVERSITY OF SOUTH FLORIDA · PI GROER, MAUREEN EDITH · 2012 to 2013
$401k
NINR NIH HHS R21 NR013094
6 · The paper itself

Abstract

backgroundThere has been a recent increase in availability of banked donor milk for feeding of preterm infants. This milk is pooled from donations to milk banks from carefully screened lactating women. The milk is then pasteurized by the Holder method to remove all microbes. The processed milk is frozen, banked, and sold to neonatal intensive care units (NICUs). The nutrient bioavailability of banked donor milk has been described, but little is known about preservation of immune components such as cytokines, chemokines, and growth factors (CCGF).

objectiveThe objective was to compare CCGF in banked donor milk with mother's own milk (MOM).

methodsAliquots (0.5 mL) were collected daily from MOM pumped by 45 mothers of NICU-admitted infants weighing < 1500 grams at birth. All daily aliquots of each mother's milk were pooled each week during 6 weeks of an infant's NICU stay or for as long as the mother provided MOM. The weekly pooled milk was measured for a panel of CCGF through multiplexing using magnetic beads and a MAGPIX instrument. Banked donor milk samples (n = 25) were handled and measured in the same way as MOM.

resultsMultiplex analysis revealed that there were levels of CCGF in banked donor milk samples comparable to values obtained from MOM after 6 weeks of lactation.

conclusionThese data suggest that many important CCGF are not destroyed by Holder pasteurization.

Indexed as

breastfeedingchemokinescytokinesdonor milkgrowth factors

Identifiers

PMID24663954
PMCPMC4175293
OpenAlexW2167027068

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.