ArticlePloS one2014
Mathematical modeling of HIV prevention measures including pre-exposure prophylaxis on HIV incidence in South Korea.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evolving landscape of economic evaluations of HIV pre-exposure prophylaxis and pre-exposure prophylaxis implementation strategies: a systematic review.Journal of the International AIDS Society · 2025Pooled it
- Korean HIV/AIDS Cohort Study: Past Achievements, Present Directions, and Future Perspectives.Jugan geon-gang gwa jilbyeong · 2025Review
- The Role of Mathematical Modelling in Predicting and Controlling Infectious Disease Outbreaks in Underserved Settings: A Systematic Review and Meta-Analysis.Public health challenges · 2025Review
- Article
- Analyses of an age structure HIV/AIDS compartmental model with optimal control theory.Scientific reports · 2025Article
- Dynamics of a two-group model for assessing the impacts of pre-exposure prophylaxis, testing and risk behaviour change on the spread and control of HIV/AIDS in an MSM population.Infectious Disease Modelling · 2024Article
- Staged HIV transmission and treatment in a dynamic model with long-term partnerships.Journal of mathematical biology · 2023Article
- Game-Theoretic Frameworks for Epidemic Spreading and Human Decision-Making: A Review.Dynamic games and applications · 2022Article
- Cost-effectiveness analysis of pre-exposure prophylaxis for the prevention of HIV in men who have sex with men in South Korea: a mathematical modelling study.Scientific reports · 2020Article
- A mathematical modelling study of HIV infection in two heterosexual age groups in Kenya.Infectious Disease Modelling · 2019Article
- Elimination prospects of the Dutch HIV epidemic among men who have sex with men in the era of preexposure prophylaxis.AIDS (London, England) · 2018Article
- Pre-exposure prophylaxis (PrEP) for MSM in low HIV incidence places: should high risk individuals be targeted?Scientific reports · 2018Article
- Article
- The Prevalence and Risk Factors of Renal Insufficiency among Korean HIV-Infected Patients: The Korea HIV/AIDS Cohort Study.Infection & chemotherapy · 2017Article
- Short Communication: HIV-1 Transmission Networks Across South Korea.AIDS research and human retroviruses · 2017Article
- Tailored combination prevention packages and PrEP for young key populations.Journal of the International AIDS Society · 2015Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundMultiple prevention measures have the possibility of impacting HIV incidence in South Korea, including early diagnosis, early treatment, and pre-exposure prophylaxis (PrEP). We investigated how each of these interventions could impact the local HIV epidemic, especially among men who have sex with men (MSM), who have become the major risk group in South Korea. A mathematical model was used to estimate the effects of each these interventions on the HIV epidemic in South Korea over the next 40 years, as compared to the current situation.
methodsWe constructed a mathematical model of HIV infection among MSM in South Korea, dividing the MSM population into seven groups, and simulated the effects of early antiretroviral therapy (ART), early diagnosis, PrEP, and combination interventions on the incidence and prevalence of HIV infection, as compared to the current situation that would be expected without any new prevention measures.
resultsOverall, the model suggested that the most effective prevention measure would be PrEP. Even though PrEP effectiveness could be lessened by increased unsafe sex behavior, PrEP use was still more beneficial than the current situation. In the model, early diagnosis of HIV infection was also effectively decreased HIV incidence. However, early ART did not show considerable effectiveness. As expected, it would be most effective if all interventions (PrEP, early diagnosis and early treatment) were implemented together.
conclusionsThis model suggests that PrEP and early diagnosis could be a very effective way to reduce HIV incidence in South Korea among MSM.
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